MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 563552 | Name: Dicyclanil
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dicyclanil is an insect growth regulator.

Chemical Structure

Dicyclanil
CAS#112636-83-6

Theoretical Analysis

MedKoo Cat#: 563552

Name: Dicyclanil

CAS#: 112636-83-6

Chemical Formula: C8H10N6

Exact Mass: 190.0967

Molecular Weight: 190.21

Elemental Analysis: C, 50.52; H, 5.30; N, 44.18

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Dicyclanil;
IUPAC/Chemical Name
4,6-Diamino-2-(cyclopropylamino)pyrimidine-5-carbonitrile
InChi Key
PKTIFYGCWCQRSX-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H10N6/c9-3-5-6(10)13-8(14-7(5)11)12-4-1-2-4/h4H,1-2H2,(H5,10,11,12,13,14)
SMILES Code
N#CC1=C(N)N=C(NC2CC2)N=C1N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 190.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: James PJ, Wardhana AH, Brown GW, Mayer DG, Urech R. Prophylactic and therapeutic efficacy of Australian-registered insecticide formulations against Old World screwworm (Chrysomya bezziana) infestation. Aust Vet J. 2017 Aug;95(8):265-272. doi: 10.1111/avj.12609. PubMed PMID: 28749021. 2: Rust MK, Hemsarth WL. Intrinsic Activity of IGRs Against Larval Cat Fleas. J Med Entomol. 2017 Mar 1;54(2):418-421. doi: 10.1093/jme/tjw201. PubMed PMID: 28011733. 3: Uddin MH, Li S, Jin Y, Choi MH, Jang JJ, Hong ST. C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine. Korean J Parasitol. 2016 Jun;54(3):281-9. doi: 10.3347/kjp.2016.54.3.281. Epub 2016 Jun 30. PubMed PMID: 27417082; PubMed Central PMCID: PMC4977786. 4: Levot GW, Langfield BJ, Aiken DJ. Survival advantage of cyromazine-resistant sheep blowfly larvae on dicyclanil- and cyromazine-treated Merinos. Aust Vet J. 2014 Nov;92(11):421-6. doi: 10.1111/avj.12251. Epub 2014 Oct 7. PubMed PMID: 25290608. 5: Baker KE, Rolfe PF, George AJ, Vanhoff KJ, Kluver PF, Bailey JN. Effective control of a suspected cyromazine-resistant strain of Lucilia cuprina using commercial spray-on formulations of cyromazine or dicyclanil. Aust Vet J. 2014 Oct;92(10):376-80. doi: 10.1111/avj.12247. Epub 2014 Aug 29. PubMed PMID: 25168341. 6: Tyrell LD, Larsen JW, Anderson N. Breech-strike on mulesed, clipped and unmulesed Merino ewes and hoggets in south-eastern Australia. Aust Vet J. 2014 Sep;92(9):348-56. doi: 10.1111/avj.12228. PubMed PMID: 25156054. 7: Cheesman MJ, Traylor MJ, Hilton ME, Richards KE, Taylor MC, Daborn PJ, Russell RJ, Gillam EM, Oakeshott JG. Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides. Insect Biochem Mol Biol. 2013 May;43(5):455-65. doi: 10.1016/j.ibmb.2013.02.003. Epub 2013 Mar 5. PubMed PMID: 23470655. 8: Hou X, Zhou D, Huai W, Beier RC, Sun Y, Lu Y, Wu G, Sun Z, Wu Y. Simultaneous determination of cyromazine and dicyclanil in animal edible tissues using UPLC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(4):660-5. doi: 10.1080/19440049.2012.760207. Epub 2013 Mar 8. PubMed PMID: 23469982. 9: Waghorn TS, McKay CH, Heath AC. The in vitro response of field strains of sheep blowflies Lucilia sericata and L. cuprina (Calliphoridae) in New Zealand to dicyclanil and triflumuron. N Z Vet J. 2013 Sep;61(5):274-80. doi: 10.1080/00480169.2012.760400. Epub 2013 Feb 27. PubMed PMID: 23441987. 10: Levot GW. Response to laboratory selection with cyromazine and susceptibility to alternative insecticides in sheep blowfly larvae from the New South Wales Monaro. Aust Vet J. 2013 Jan-Feb;91(1-2):61-4. doi: 10.1111/avj.12011. Epub 2012 Dec 23. PubMed PMID: 23356375. 11: Levot GW. Cyromazine resistance detected in Australian sheep blowfly. Aust Vet J. 2012 Nov;90(11):433-7. doi: 10.1111/j.1751-0813.2012.00984.x. Epub 2012 Sep 19. PubMed PMID: 23106323. 12: Larsen JW, Tyrell LD, Anderson N. Prevalence of breech-strike in mulesed, clipped and unmulesed Merino hoggets in south-eastern Australia. Aust Vet J. 2012 May;90(5):158-66. doi: 10.1111/j.1751-0813.2012.00914.x. Erratum in: Aust Vet J. 2012 Jun;90(6):202. PubMed PMID: 22510074. 13: Walters M, Wall R. Evaluation of dicyclanil (CLiKZiN®) treatment for the early-season protection of ewes against blowfly strike. Vet Parasitol. 2012 Aug 13;188(1-2):200-2. doi: 10.1016/j.vetpar.2012.03.016. Epub 2012 Mar 20. PubMed PMID: 22494939. 14: Jin M, Dewa Y, Kawai M, Nishimura J, Saegusa Y, Kemmochi S, Harada T, Shibutani M, Mitsumori K. The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice. J Toxicol Sci. 2010 Feb;35(1):69-78. PubMed PMID: 20118626. 15: James PJ, Cramp AP, Winkleman J, Mcphie R, Brown GW. Strategic use of crutching and dicyclanil to protect unmulesed sheep against breech strike. Aust Vet J. 2009 Apr;87(4):138-41. doi: 10.1111/j.1751-0813.2009.00408.x. PubMed PMID: 19335467. 16: Matsumoto S, Jin M, Dewa Y, Nishimura J, Moto M, Murata Y, Shibutani M, Mitsumori K. Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice. J Toxicol Sci. 2009 Feb;34(1):109-18. PubMed PMID: 19182440. 17: Umemura T, Kuroiwa Y, Tasaki M, Okamura T, Ishii Y, Kodama Y, Nohmi T, Mitsumori K, Nishikawa A, Hirose M. Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice. Mutat Res. 2007 Sep 1;633(1):46-54. Epub 2007 May 18. PubMed PMID: 17581771. 18: Daborn PJ, Lumb C, Boey A, Wong W, Ffrench-Constant RH, Batterham P. Evaluating the insecticide resistance potential of eight Drosophila melanogaster cytochrome P450 genes by transgenic over-expression. Insect Biochem Mol Biol. 2007 May;37(5):512-9. Epub 2007 Mar 2. PubMed PMID: 17456446. 19: Hempel H, Scheffczyk A, Schallnass HJ, Lumaret JP, Alvinerie M, Römbke J. Toxicity of four veterinary parasiticides on larvae of the dung beetle Aphodius constans in the laboratory. Environ Toxicol Chem. 2006 Dec;25(12):3155-63. PubMed PMID: 17220084. 20: Moto M, Okamura M, Muguruma M, Ito T, Jin M, Kashida Y, Mitsumori K. Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice. Toxicol Pathol. 2006;34(6):744-51. PubMed PMID: 17162532.