MedKoo Cat#: 598915 | Name: Lincospectin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lincospectin is a bioactive chemical.

Chemical Structure

Lincospectin
Lincospectin
CAS#57456-42-5

Theoretical Analysis

MedKoo Cat#: 598915

Name: Lincospectin

CAS#: 57456-42-5

Chemical Formula: C32H60N4O17S2

Exact Mass:

Molecular Weight: 836.96

Elemental Analysis: C, 45.92; H, 7.23; N, 6.69; O, 32.50; S, 7.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lincospectin;
IUPAC/Chemical Name
sulfuric acid compound with (2S,4S)-N-((1R,2R)-2-hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-4-isopropyl-1-methylpyrrolidine-2-carboxamide and (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-benzo[b]pyrano[2,3-e][1,4]dioxin-4-one (1:1:1)
InChi Key
ONXOKWFYBIQOFQ-VSXSCALHSA-N
InChi Code
InChI=1S/C18H34N2O6S.C14H24N2O7.H2O4S/c1-8(2)10-6-11(20(4)7-10)17(25)19-12(9(3)21)16-14(23)13(22)15(24)18(26-16)27-5;1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;1-5(2,3)4/h8-16,18,21-24H,6-7H2,1-5H3,(H,19,25);5,7-13,15-16,18-20H,4H2,1-3H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14-,15-,16-,18-;5-,7-,8+,9+,10+,11-,12-,13+,14+;/m11./s1
SMILES Code
CN[C@H]1[C@@H](O)[C@@H](NC)[C@H](O)[C@@H]2[C@@H]1O[C@](C(C[C@@H](C)O3)=O)(O)[C@@H]3O2.O=S(O)(O)=O.CS[C@@H]4[C@H](O)[C@@H](O)[C@@H](O)[C@@H]([C@@H]([C@H](O)C)NC([C@@H]5C[C@@H](C(C)C)CN5C)=O)O4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 836.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 2957189. 4: Krause D, Weitze KF, Waberski D. [The sperm compatibility of lincospectin in the framework of the Federal Republic of Germany customary bull sperm preservation methods with the use of a Tris egg yolk thinner (clinical short report)]. Dtsch Tierarztl Wochenschr. 1989 Nov-Dec;96(10):508, 510. German. PubMed PMID: 2532126. 5: Yang CY, Lin CN, Lin CF, Chang TC, Chiou MT. Serotypes, antimicrobial susceptibility, and minimal inhibitory concentrations of Actionbacillus pleuropneumoniae isolated from slaughter pigs in Taiwan (2002-2007). J Vet Med Sci. 2011 Feb;73(2):205-8. Epub 2010 Oct 8. PubMed PMID: 20948169. 6: Tsiloyiannis VK, Kyriakis SC, Vlemmas J, Sarris K. The effect of organic acids on the control of porcine post-weaning diarrhoea. Res Vet Sci. 2001 Jun;70(3):287-93. PubMed PMID: 11676629. 7: Stephens CP, Hampson DJ. Intestinal spirochete infections of chickens: a review of disease associations, epidemiology and control. Anim Health Res Rev. 2001 Jun;2(1):83-91. Review. PubMed PMID: 11708751. 8: Askari Badouei M, Zahraei Salehi T, Koochakzadeh A, Kalantari A, Tabatabaei S. Molecular characterization, genetic diversity and antibacterial susceptibility of Escherichia coli encoding Shiga toxin 2f in domestic pigeons. Lett Appl Microbiol. 2014 Oct;59(4):370-6. doi: 10.1111/lam.12288. Epub 2014 Jun 18. PubMed PMID: 24863542. 9: Werner-Tutschku M, Schuh M, Awad-Masalmeh M, Krassnig G, Schweighardt H, Truschner K. [Clinical and microbiological investigations of atrophic rhinitis of Upper Austrian swine herds]. Dtsch Tierarztl Wochenschr. 1997 Sep;104(9):344-9. German. PubMed PMID: 9410721. 10: Truscott RB, Abreo C. Antibiotics for elimination of mycoplasmas and ureaplasma from bovine semen. J Dairy Sci. 1977 Jun;60(6):954-60. PubMed PMID: 141466. 11: Pfützner H. [The "in vitro" effect of antibiotics on mycoplasmas under conditions of the preparation of bull sperm]. Arch Exp Veterinarmed. 1989;43(5):725-8. German. PubMed PMID: 2619467. 12: Andrabi SM, Khan LA, Shahab M. Isolation of bacteria in semen and evaluation of antibiotics in extender for cryopreservation of buffalo (Bubalus bubalis) bull spermatozoa. Andrologia. 2016 Dec;48(10):1166-1174. doi: 10.1111/and.12555. Epub 2016 Feb 19. PubMed PMID: 26892806. 13: Stepniewska K, Urbaniak K, Markowska-Daniel I. Phenotypic and genotypic characterization of Bordetella bronchiseptica strains isolated from pigs in Poland. Pol J Vet Sci. 2014;17(1):71-7. PubMed PMID: 24724472. 14: Truscott RB, Onoviran O, Ruhnke HL, Fish NA, Barker CA. In vitro antimicrobial sensitivity of Mycoplasmas isolated from the bovine genital tract. Can J Comp Med. 1975 Oct;39(4):416-20. PubMed PMID: 169970; PubMed Central PMCID: PMC1277489. 15: Marcus S, Ziv G, Glickman A, Ozbonfil D, Bartoov B, Klein A. Lincomycin and spectinomycin in the treatment of breeding rams with semen contaminated with ureaplasmas. Res Vet Sci. 1994 Nov;57(3):393-4. PubMed PMID: 7871264. 16: Guyot A, Jarrett B, Sanvee L, Dore D. Antimicrobial resistance of Neisseria gonorrhoeae in Liberia. Trans R Soc Trop Med Hyg. 1998 Nov-Dec;92(6):670-4. PubMed PMID: 10326119. 17: Alavi-Shoushtari SM, Ahmadi M, Shahvarpour S, Kolahian S. Effects of tiamulin, neomycin, tetracycline, fluorophenicol, penicillin G, Linco-Spectin, erythromycin and oxytetracycline on controlling bacterial contaminations of the river buffalo (Buballus bubalis) semen. Pak J Biol Sci. 2007 Sep 15;10(18):3200-4. PubMed PMID: 19090126. 18: Hamdy AH. Therapeutic effect of Linco-Spectin on airsacculitis in chickens. Avian Dis. 1970 Nov;14(4):706-14. PubMed PMID: 4926234. 19: Hamdy AH, Kleven SH, McCune EL. Efficacy of Linco-Spectin water medication on Mycoplasma synoviae Airsacculitis in broilers. Avian Dis. 1976 Jan-Mar;20(1):118-25. PubMed PMID: 130899. 20: Chang CF, Chang LC, Chang YF, Chen M, Chiang TS. Antimicrobial susceptibility of Actinobacillus pleuropneumoniae, Escherichia coli, and Salmonella choleraesuis recovered from Taiwanese swine. J Vet Diagn Invest. 2002 Mar;14(2):153-7. PubMed PMID: 11939337.