Inocoterone acetate | CAS#83646-86-0 | antiandrogen

MedKoo Cat#: 461516 | Name: Inocoterone acetate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and has antiandrogenic activity in animal models.

Chemical Structure

Inocoterone acetate

CAS#83646-86-0

Theoretical Analysis

MedKoo Cat#: 461516

Name: Inocoterone acetate

CAS#: 83646-86-0

Chemical Formula: C18H26O3

Exact Mass: 290.1882

Molecular Weight: 290.40

Elemental Analysis: C, 74.45; H, 9.02; O, 16.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Inocoterone acetate; RU 38882; RU-38882; RU38882; RU 882; RU-882; RU882;

IUPAC/Chemical Name

(3S,3aS,9aS,9bS)-6-ethyl-3a-methyl-7-oxo-2,3,3a,4,5,7,8,9,9a,9b-decahydro-1H-cyclopenta[a]naphthalen-3-yl acetate

InChi Key

JDLUQDYTLSPFGS-FZCLSBEQSA-N

InChi Code

InChI=1S/C18H26O3/c1-4-12-13-9-10-18(3)15(14(13)5-7-16(12)20)6-8-17(18)21-11(2)19/h14-15,17H,4-10H2,1-3H3/t14-,15+,17+,18+/m1/s1

SMILES Code

O=C(CC1)C(CC)=C2[C@]1([H])[C@]3([H])CC[C@H](OC(C)=O)[C@@]3(C)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 290.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lookingbill DP, Abrams BB, Ellis CN, Jegasothy BV, Lucky AW, Ortiz-Ferrer LC, Savin RC, Shupack JL, Stiller MJ, Zone JJ, et al. Inocoterone and acne. The effect of a topical antiandrogen: results of a multicenter clinical trial. Arch Dermatol. 1992 Sep;128(9):1197-200. PubMed PMID: 1387778. 2: Bouton MM, Lecaque D, Secchi J, Tournemine C. Effect of a new topically active antiandrogen (RU 38882) on the rat sebaceous gland: comparison with cyproterone acetate. J Invest Dermatol. 1986 Feb;86(2):163-7. PubMed PMID: 2943819. 3: Matias JR, Gaillard M. Local inhibition of sebaceous gland growth by topically applied RU 58841. Ann N Y Acad Sci. 1995 Jun 12;761:56-65. PubMed PMID: 7625751. 4: Cunliffe WJ, Bottomley WW. Antiandrogens and acne. A topical approach? Arch Dermatol. 1992 Sep;128(9):1261-4. PubMed PMID: 1387779. 5: Daniel JY, Abalain JH, Amet Y, Di Stefano S, Berthou F, Tea K, Floch HH, Bouton MM, Secchi J. The quail uropygial gland for assays of systemic antiandrogen side-effects of topical drugs. Br J Dermatol. 1986 Aug;115 Suppl 31:33-5. PubMed PMID: 3741798. 6: Secchi J, Lecaque D, Bouton MM. Morphometric evaluation of local anti-androgenic activity on the rat sebaceous gland. Br J Dermatol. 1984 Jul;111 Suppl 27:178-9. PubMed PMID: 6234921.