Synonym
Ligupurpuroside C; Lipedoside A I;
IUPAC/Chemical Name
(2R,3R,4S,5R,6R)-5-(3,4-dihydroxyphenethyl)-5,6-dihydroxy-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(4-hydroxyphenyl)acrylate
InChi Key
WLLWOVDIXHUEGL-HGPKRGIGSA-N
InChi Code
InChI=1S/C29H36O14/c1-14-22(35)23(36)24(37)27(40-14)43-26-25(42-21(34)9-5-15-2-6-17(31)7-3-15)20(13-30)41-28(38)29(26,39)11-10-16-4-8-18(32)19(33)12-16/h2-9,12,14,20,22-28,30-33,35-39H,10-11,13H2,1H3/b9-5+/t14-,20+,22-,23+,24+,25+,26-,27-,28+,29+/m0/s1
SMILES Code
O[C@H]1[C@]([C@H]([C@H](OC(/C=C/C2=CC=C(O)C=C2)=O)[C@@H](CO)O1)O[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)(CCC4=CC=C(O)C(O)=C4)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
608.59
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Chen QQ, Guo JR, Feng SM, Wang CY, Zhang W. Quantitation of ligupurpurosides B and C in rat plasma using HPLC-MS/MS. Chin J Nat Med. 2016 Jun;14(6):473-80. doi: 10.1016/S1875-5364(16)30045-0. PubMed PMID: 27473966.
2: He ZD, Lau KM, But PP, Jiang RW, Dong H, Ma SC, Fung KP, Ye WC, Sun HD. Antioxidative glycosides from the leaves of Ligustrum robustum. J Nat Prod. 2003 Jun;66(6):851-4. PubMed PMID: 12828473.
3: Yang R, Chu X, Sun L, Kang Z, Ji M, Yu Y, Liu Y, He Z, Gao N. Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet. Phytother Res. 2018 Apr;32(4):715-722. doi: 10.1002/ptr.6023. Epub 2018 Feb 22. PubMed PMID: 29468762.
