RS 5773 | CAS#129173-57-5 | benzothiazepine derivative

MedKoo Cat#: 461484 | Name: RS 5773

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RS 5773 is a benzothiazepine derivative that has antianginal effects.

Chemical Structure

RS 5773

CAS#129173-57-5

Theoretical Analysis

MedKoo Cat#: 461484

Name: RS 5773

CAS#: 129173-57-5

Chemical Formula: C27H31ClN2O4S2

Exact Mass: 546.1414

Molecular Weight: 547.12

Elemental Analysis: C, 59.27; H, 5.71; Cl, 6.48; N, 5.12; O, 11.70; S, 11.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RS 5773; RS-5773; RS5773;

IUPAC/Chemical Name

(2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-8-(thiophen-2-ylmethyl)-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate hydrochloride

InChi Key

UUYRJDKLOCCAMI-QGLFPKSOSA-N

InChi Code

InChI=1S/C27H30N2O4S2.ClH/c1-18(30)33-25-26(20-8-10-21(32-4)11-9-20)35-24-17-19(16-22-6-5-15-34-22)7-12-23(24)29(27(25)31)14-13-28(2)3;/h5-12,15,17,25-26H,13-14,16H2,1-4H3;1H/t25-,26+;/m1./s1

SMILES Code

O=C1[C@H](OC(C)=O)[C@H](C2=CC=C(OC)C=C2)SC3=CC(CC4=CC=CS4)=CC=C3N1CCN(C)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 547.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shiga H, Miyake S, Fukuda N, Yorikane R, Koike H. Antianginal effect of RS-5773, a diltiazem congener, in the methacholine-induced anginal model in rats. Jpn J Pharmacol. 1996 Dec;72(4):365-74. PubMed PMID: 9015745. 2: Shiga H, Miyake S, Ideka M, Ito Y, Yanagisawa H, Koike H. Pharmacological profile of a novel 1,5-benzothiazepine calcium antagonist. Arzneimittelforschung. 1992 May;42(5):617-21. PubMed PMID: 1530673.