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MedKoo Cat#: 592725 | Name: Altromycin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Altromycin A is an anticancer drug.

Chemical Structure

Altromycin A
Altromycin A
CAS#128439-47-4

Theoretical Analysis

MedKoo Cat#: 592725

Name: Altromycin A

CAS#: 128439-47-4

Chemical Formula: C46H57NO18

Exact Mass: 911.3576

Molecular Weight: 911.95

Elemental Analysis: C, 60.59; H, 6.30; N, 1.54; O, 31.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Altromycin A
IUPAC/Chemical Name
Octonic acid, 3,7-anhydro-8-deoxy-2-C-(2-(2,3-dimethyloxiranyl)-7,12-dihydro-11-hydroxy-4,7,12-trioxo-10-(2,3,6-trideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-D-ribo-hexopyranosyl)-3-C-methyl-3-(methylamino)-alpha-L-lyxo-hexopyranosyl)-4H-anthra(1,2-b)pyran-5-yl)-5-O-methyl-, methyl ester
InChi Key
PDEWBVUBUCMSFD-UHFFFAOYSA-N
InChi Code
InChI=1S/C46H57NO18/c1-17-32(49)38(57-8)27(16-60-17)63-41-19(3)61-26(15-44(41,5)47-7)21-11-12-22-29(35(21)52)36(53)30-23(34(22)51)13-24(31-25(48)14-28(64-39(30)31)45(6)20(4)65-45)46(56,43(55)59-10)42-37(54)40(58-9)33(50)18(2)62-42/h11-14,17-20,26-27,32-33,37-38,40-42,47,49-50,52,54,56H,15-16H2,1-10H3
SMILES Code
CC1C(C(C(CO1)OC2C(OC(CC2(C)NC)c3ccc4c(c3O)C(=O)c5c(cc(c6c5oc(cc6=O)C7(C(O7)C)C)C(C8C(C(C(C(O8)C)O)OC)O)(C(=O)OC)O)C4=O)C)OC)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 911.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Fei Z, McDonald FE. Synthesis of the aglycones of altromycins and kidamycin from a common intermediate. Org Lett. 2005 Aug 18;7(17):3617-20. PubMed PMID: 16092833; PubMed Central PMCID: PMC1388187. 2: Jackson M, Karwowski JP, Theriault RJ, Hardy DJ, Swanson SJ, Barlow GJ, Tillis PM, McAlpine JB. Altromycins, novel pluramycin-like antibiotics. I. Taxonomy of the producing organism, fermentation and antibacterial activity. J Antibiot (Tokyo). 1990 Mar;43(3):223-8. PubMed PMID: 2324007. 3: Brill GM, McAlpine JB, Whittern DN, Buko AM. Altromycins, novel pluramycin-like antibiotics. II. Isolation and elucidation of structure. J Antibiot (Tokyo). 1990 Mar;43(3):229-37. PubMed PMID: 2324008.