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MedKoo Cat#: 592721 | Name: Aldrin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aldrin is an organochlorine insecticide that was widely used until the 1990s, when it was banned in most countries. Aldrin is a member of the so-called "classic organochlorines" (COC) group of pesticides. COCs enjoyed a very sharp rise in popularity during and after The Second World War.

Chemical Structure

Aldrin
CAS#309-00-2

Theoretical Analysis

MedKoo Cat#: 592721

Name: Aldrin

CAS#: 309-00-2

Chemical Formula: C12H8Cl6

Exact Mass: 361.8757

Molecular Weight: 364.90

Elemental Analysis: C, 39.50; H, 2.21; Cl, 58.29

Price and Availability

Size Price Availability Quantity
25mg USD 315.00 2 Weeks
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Related CAS #
No Data
Synonym
Aldrin; NSC 8937; NSC-8937; NSC8937
IUPAC/Chemical Name
1,4:5,8-Dimethanonaphthalene, 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a-hexahydro-, (1alpha,4alpha,4abeta,5alpha,8alpha,8abeta)-
InChi Key
QBYJBZPUGVGKQQ-SEIHLVFNSA-N
InChi Code
InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10-,11+
SMILES Code
ClC1(Cl)[C@@]2(Cl)C(Cl)=C(Cl)[C@]1(Cl)[C@@]3([H])[C@](C4)([H])C=C[C@]4([H])[C@@]23[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 364.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bozcaarmutlu A, Turna S, Sapmaz C, Arinc E, Yenisoy-Karakaş S. Aldrin epoxidation in flathead mullet (Mugil cephalus): possible involvement of CYP1A and CYP3A. J Biochem Mol Toxicol. 2014 Jun;28(6):271-80. doi: 10.1002/jbt.21563. Epub 2014 Apr 22. PubMed PMID: 24756956. 2: Hooker EP, Fulcher KG, Gibb HJ. Aldrin and dieldrin: a reevaluation of the cancer and noncancer dose-response assessments. Risk Anal. 2014 May;34(5):865-78. PubMed PMID: 24955469. 3: Ali M, Kazmi AA, Ahmed N. Study on effects of temperature, moisture and pH in degradation and degradation kinetics of aldrin, endosulfan, lindane pesticides during full-scale continuous rotary drum composting. Chemosphere. 2014 May;102:68-75. doi: 10.1016/j.chemosphere.2013.12.022. Epub 2014 Jan 25. PubMed PMID: 24468112. 4: Ali M, Gani KM, Kazmi AA, Ahmed N. Degradation of aldrin and endosulfan in rotary drum and windrow composting. J Environ Sci Health B. 2016;51(5):278-86. doi: 10.1080/03601234.2015.1128739. Epub 2016 Feb 1. PubMed PMID: 26828724. 5: Tobiszewski M, Orłowski A. Multicriteria decision analysis in ranking of analytical procedures for aldrin determination in water. J Chromatogr A. 2015 Mar 27;1387:116-22. doi: 10.1016/j.chroma.2015.02.009. Epub 2015 Feb 11. PubMed PMID: 25704773. 6: Li X, Dai X, Yin X, Li M, Zhao Y, Zhou J, Huang T, Li H. Impurity analysis of pure aldrin using heart-cut multi-dimensional gas chromatography-mass spectrometry. J Chromatogr A. 2013 Feb 15;1277:69-75. doi: 10.1016/j.chroma.2012.12.038. Epub 2013 Jan 3. PubMed PMID: 23332869. 7: Mustafa M, Pathak R, Tripathi AK, Ahmed RS, Guleria K, Banerjee BD. Maternal and cord blood levels of aldrin and dieldrin in Delhi population. Environ Monit Assess. 2010 Dec;171(1-4):633-8. doi: 10.1007/s10661-010-1307-9. Epub 2010 Mar 2. PubMed PMID: 20195752. 8: Xiao P, Mori T, Kamei I, Kiyota H, Takagi K, Kondo R. Novel metabolic pathways of organochlorine pesticides dieldrin and aldrin by the white rot fungi of the genus Phlebia. Chemosphere. 2011 Sep;85(2):218-24. doi: 10.1016/j.chemosphere.2011.06.028. Epub 2011 Jul 2. PubMed PMID: 21724225. 9: Rowland GA, Bausch AR, Grannas AM. Photochemical processing of aldrin and dieldrin in frozen aqueous solutions under arctic field conditions. Environ Pollut. 2011 May;159(5):1076-84. doi: 10.1016/j.envpol.2011.02.026. Epub 2011 Mar 10. PubMed PMID: 21396757. 10: Carvalho WA, Matos GB, Cruz SL, Rodrigues DS. [Acute poisoning by aldrin: relationship between serum levels and toxic effects in humans]. Rev Saude Publica. 1990 Feb;24(1):39-46. Portuguese. PubMed PMID: 2218374. 11: Akkermans LM, van den Bercken J, van der Zalm J. Effects of aldrin-transdiol on neuromuscular facilitation and depression. Eur J Pharmacol. 1975 Apr;31(2):166-75. PubMed PMID: 238851. 12: Jamaluddin S, Poddar MK. Aldrin-induced locomotor activity: possible involvement of the central GABAergic-cholinergic-dopaminergic interaction. Pol J Pharmacol. 2001 Jan-Feb;53(1):21-30. PubMed PMID: 11785907. 13: Stevenson DE, Walborg EF Jr, North DW, Sielken RL Jr, Ross CE, Wright AS, Xu Y, Kamendulis LM, Klaunig JE. Monograph: reassessment of human cancer risk of aldrin/dieldrin. Toxicol Lett. 1999 Oct 5;109(3):123-86. Review. PubMed PMID: 10555138. 14: Graham MJ, Williams FM, Rawlins MD. Metabolism of aldrin to dieldrin by rat skin following topical application. Food Chem Toxicol. 1991 Oct;29(10):707-11. PubMed PMID: 1959824. 15: Grannas AM, Pagano LP, Pierce BC, Bobby R, Fede A. Role of dissolved organic matter in ice photochemistry. Environ Sci Technol. 2014 Sep 16;48(18):10725-33. doi: 10.1021/es5023834. Epub 2014 Sep 3. PubMed PMID: 25157605. 16: Scheunert I, Kohli J, Kaul R, Klein W. Fate of [14C]aldrin in crop rotation under outdoor conditions. Ecotoxicol Environ Saf. 1977 Dec;1(3):365-85. PubMed PMID: 617099. 17: Buser HR, Müller MD, Buerge IJ, Poiger T. Composition of aldrin, dieldrin, and photodieldrin enantiomers in technical and environmental samples. J Agric Food Chem. 2009 Aug 26;57(16):7445-52. doi: 10.1021/jf901049c. PubMed PMID: 19645510. 18: Jamaluddin SK, Poddar MK. Role of brain regional GABA: aldrin-induced stimulation of locomotor activity in rat. Neurochem Res. 2001 Apr;26(4):439-51. PubMed PMID: 11495356. 19: Teixeira D, Pestana D, Santos C, Correia-Sá L, Marques C, Norberto S, Meireles M, Faria A, Silva R, Faria G, Sá C, Freitas P, Taveira-Gomes A, Domingues V, Delerue-Matos C, Calhau C, Monteiro R. Inflammatory and cardiometabolic risk on obesity: role of environmental xenoestrogens. J Clin Endocrinol Metab. 2015 May;100(5):1792-801. doi: 10.1210/jc.2014-4136. Epub 2015 Apr 8. PubMed PMID: 25853792. 20: Nair A, Dureja P, Pillai MK. Aldrin and dieldrin residues in human fat, milk and blood serum collected from Delhi. Hum Exp Toxicol. 1992 Jan;11(1):43-5. PubMed PMID: 1354459.