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MedKoo Cat#: 598822 | Name: Licam-C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Licam-C is a bioactive chemical.

Chemical Structure

Licam-C
Licam-C
CAS#75956-68-2

Theoretical Analysis

MedKoo Cat#: 598822

Name: Licam-C

CAS#: 75956-68-2

Chemical Formula: C31H31N3O15

Exact Mass: 685.1755

Molecular Weight: 685.59

Elemental Analysis: C, 54.31; H, 4.56; N, 6.13; O, 35.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Licam-C;
IUPAC/Chemical Name
4-((4-(4-carboxy-2,3-dihydroxybenzamido)butyl)(3-(4-carboxy-2,3-dihydroxybenzamido)propyl)carbamoyl)-2,3-dihydroxybenzoic acid
InChi Key
XPKJIQPHKHFKFW-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H31N3O15/c35-20-14(4-7-17(23(20)38)29(44)45)26(41)32-10-1-2-12-34(28(43)16-6-9-19(31(48)49)25(40)22(16)37)13-3-11-33-27(42)15-5-8-18(30(46)47)24(39)21(15)36/h4-9,35-40H,1-3,10-13H2,(H,32,41)(H,33,42)(H,44,45)(H,46,47)(H,48,49)
SMILES Code
O=C(O)C1=CC=C(C(N(CCCCNC(C2=CC=C(C(O)=O)C(O)=C2O)=O)CCCNC(C3=CC=C(C(O)=O)C(O)=C3O)=O)=O)C(O)=C1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 685.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Stradling GN, Stather JW, Gray SA, Moody JC, Ellender M, Hodgson A. Efficacies of LICAM(C) and DTPA for the decorporation of inhaled transportable forms of plutonium and americium from the rat. Hum Toxicol. 1986 Mar;5(2):77-84. PubMed PMID: 3514430. 2: Volf V, Taylor DM, Brandau W, Schlenker P. The effect of pure LICAM(C) on the retention of plutonium-238 in mice and rats. Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Aug;50(2):205-11. PubMed PMID: 3488281. 3: Gerasimo P, Duserre C, Ducousso R, Metivier H. [Value of standard Licam (C) in plutonium radiocontamination]. Ann Pharm Fr. 1987;45(3):189-94. French. PubMed PMID: 3434970. 4: Szot Z, Rochalska M, Wojewódzka M, Chimiak A, Przychodzen W. Removal of 239Pu from mice with 3,4,3 LICAM(C) or N,N',N'',N'''-tetra-(2,3-dihydroxybenzoyl)-spermine. Radiat Environ Biophys. 1986;25(1):31-5. PubMed PMID: 3754971. 5: Stradling GN, Stather JW, Gray SA, Moody JC, Ellender M, Hodgson A. The efficacies of pure LICAM(C) and DTPA for enhancing the elimination of plutonium-238 and americium-241 from rats after their inhalation as nitrate. Exp Pathol. 1989;37(1-4):83-8. PubMed PMID: 2637176. 6: Lloyd RD, Bruenger FW, Mays CW, Atherton DR, Jones CW, Taylor GN, Stevens W, Durbin PW, Jeung N, Jones ES, et al. Removal of Pu and am from beagles and mice by 3,4,3-LICAM(C) or 3,4,3-LICAM(S). Radiat Res. 1984 Jul;99(1):106-28. PubMed PMID: 6547537. 7: Durbin PW, Jeung N, Jones ES, Weitl FL, Raymond KN. Specific sequestering agents for the actinides: 10. Enhancement of 238Pu elimination from mice by poly(catechoylamide) ligands. Radiat Res. 1984 Jul;99(1):85-105. PubMed PMID: 6547538. 8: Volf V. Chelation therapy of incorporated plutonium-238 and americium-241: comparison of LICAM(C), DTPA and DFOA in rats, hamsters and mice. Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Mar;49(3):449-62. PubMed PMID: 3485592. 9: Durbin PW, White DL, Jeung NL, Weitl FL, Uhlir LC, Jones ES, Bruenger FW, Raymond KN. Chelation of 238Pu(IV) in vivo by 3,4,3-LICAM(C): effects of ligand methylation and pH. Health Phys. 1989 Jun;56(6):839-55. PubMed PMID: 2722507. 10: Stradling GN, Stather JW, Gray SA, Moody JC, Ellender M, Hodgson A, Volf V, Taylor DM, Wirth P, Gaskin PW. The efficacies of pure LICAM(C) and DTPA on the retention of plutonium-238 and americium-241 in rats after their inhalation as nitrate and intravenous injection as citrate. Int J Radiat Biol. 1989 Oct;56(4):503-14. PubMed PMID: 2571662. 11: Gerasimo P, Duserre C, Metivier H. Biological behaviour of Pu administered to animals as Pu-standard LICAM(C) complex: therapeutical attempts to decrease Pu kidney burden. Hum Toxicol. 1986 Sep;5(5):309-18. PubMed PMID: 3770768. 12: Mays CW, Lloyd RD, Jones CW, Bruenger FW, Taylor GN, Durbin PW, White D, Raymond KN. Decorporation of Pu and Am from beagles with delayed daily injections of 3,4,3-LICAM(C) or Zn-DTPA. Health Phys. 1986 Apr;50(4):530-4. PubMed PMID: 3754241. 13: Duffield JR, Taylor DM, Proctor SA. The binding of plutonium to transferrin in the presence of tri-n-butyl phosphate or nitrate and its release by diethylenetriaminepenta-acetate and the tetrameric catechoylamide ligand LICAMC(C). Int J Nucl Med Biol. 1986;12(6):483-7. PubMed PMID: 3754852. 14: Cazoulat A, Gerasimo P, Burgada R, Bailly T. Topological structure activity analysis of diphosphonates in the elimination of radionuclides from body. Ann Pharm Fr. 1997;55(3):125-34. PubMed PMID: 9239861. 15: Moerlein SM, Welch MJ, Raymond KN. Use of tricatecholamide ligands to alter the biodistribution of gallium-67: concise communication. J Nucl Med. 1982 Jun;23(6):501-6. PubMed PMID: 6951964. 16: Luo MC, Volf V. Testing of methyleneiminodiacetic-catechol and other aromatic chelating agents for decorporation of 238Pu and 241Am in rats. Int J Radiat Biol. 1989 Apr;55(4):679-88. PubMed PMID: 2564876. 17: Szot Z, Rochalska M, Chomiczewski K, Chimiak A, Przychodzeń W. Efficacy and toxicity of N,N',N",N"'-tetra(2,3,4-trihydroxybenzoyl)-spermine for decorporation of 239Pu from mice. Int J Radiat Biol. 1989 Jan;55(1):141-9. PubMed PMID: 2562970. 18: Metivier H, Masse R, Durbin PW, Raymond KN. Promotion by tetrameric catechoylamide ligands and CaNa3-DTPA of the dissociation in vitro of the Pu-transferrin complex formed after intravenous injection of Pu-tri-N-butylphosphate. Health Phys. 1985 Dec;49(6):1302-5. PubMed PMID: 3841100.