MedKoo Cat#: 563520 | Name: NMP-7

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NMP-7 is a non-selective agonist of the CB1 and CB2 cannabinoid receptors that acts by blocking T-type calcium channels.

Chemical Structure

NMP-7
CAS#1358039-07-2

Theoretical Analysis

MedKoo Cat#: 563520

Name: NMP-7

CAS#: 1358039-07-2

Chemical Formula: C23H28N2O

Exact Mass: 348.2202

Molecular Weight: 348.49

Elemental Analysis: C, 79.27; H, 8.10; N, 8.04; O, 4.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
NMP-7; NMP 7; NMP7;
IUPAC/Chemical Name
(9-pentyl-9H-carbazol-3-yl)(piperidin-1-yl)methanone
InChi Key
NZEVKZAEMSMLMC-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H28N2O/c1-2-3-7-16-25-21-11-6-5-10-19(21)20-17-18(12-13-22(20)25)23(26)24-14-8-4-9-15-24/h5-6,10-13,17H,2-4,7-9,14-16H2,1H3
SMILES Code
O=C(C1=CC2=C(C=C1)N(CCCCC)C3=C2C=CC=C3)N4CCCCC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 348.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Berger ND, Gadotti VM, Petrov RR, Chapman K, Diaz P, Zamponi GW. NMP-7 inhibits chronic inflammatory and neuropathic pain via block of Cav3.2 T-type calcium channels and activation of CB2 receptors. Mol Pain. 2014 Dec 6;10:77. doi: 10.1186/1744-8069-10-77. PubMed PMID: 25481027; PubMed Central PMCID: PMC4271433. 2: You H, Gadotti VM, Petrov RR, Zamponi GW, Diaz P. Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands. Mol Pain. 2011 Nov 17;7:89. doi: 10.1186/1744-8069-7-89. PubMed PMID: 22093952; PubMed Central PMCID: PMC3250956. 3: Little MA, Ronson TK, Hardie MJ. New coordination polymers with extended arm cyclotriguaiacyclene ligands: 1D chains, and interpenetrating or polycatenating 2D (4(2).6(2))(4.6(2))2 networks. Dalton Trans. 2011 Dec 7;40(45):12217-27. doi: 10.1039/c1dt10662g. Epub 2011 Aug 25. PubMed PMID: 21869979.