Synonym
LG 50214; LG-50214; LG50214; LG 50,214; LG-50,214; LG50,214;
IUPAC/Chemical Name
(E)-1-(2-ethylmorpholino)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
InChi Key
BAZBPLVEWJXYSU-VOTSOKGWSA-N
InChi Code
InChI=1S/C18H25NO5/c1-5-14-12-19(8-9-24-14)17(20)7-6-13-10-15(21-2)18(23-4)16(11-13)22-3/h6-7,10-11,14H,5,8-9,12H2,1-4H3/b7-6+
SMILES Code
CCC1CN(C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O)CCO1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Biological target:
LG 50214 is a bioactive chemical.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
335.47
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kim HJ, Kim DK, Sohn TS, Lee JH, Lee GH. A laparoscopic gastrectomy approach decreases the incidence and severity of emergence agitation after sevoflurane anesthesia. J Anesth. 2015 Apr;29(2):223-8. doi: 10.1007/s00540-014-1905-8. Epub 2014 Aug 14. PubMed PMID: 25120246.
2: Feng X, Wang X, Yu X, Zhang X, Lu C, Sun X, Tong J. Microsatellite-centromere mapping in common carp through half-tetrad analysis in diploid meiogynogenetic families. Chromosoma. 2015 Mar;124(1):67-79. doi: 10.1007/s00412-014-0485-6. Epub 2014 Aug 30. PubMed PMID: 25171918.
3: Noiseux I, Gauthier SF, Turgeon SL. Interactions between bovine beta-lactoglobulin and peptides under different physicochemical conditions. J Agric Food Chem. 2002 Mar 13;50(6):1587-92. PubMed PMID: 11879041.
4: Lensmeyer GL, Gidal BE, Wiebe DA. Optimized high-performance liquid chromatographic method for determination of lamotrigine in serum with concomitant determination of phenytoin, carbamazepine, and carbamazepine epoxide. Ther Drug Monit. 1997 Jun;19(3):292-300. PubMed PMID: 9200770.
5: Lu Y, Aguirre AA, Wang Y, Zeng L, Loh PC, Yanagihara R. Viral susceptibility of newly established cell lines from the Hawaiian monk seal Monachus schauinslandi. Dis Aquat Organ. 2003 Dec 29;57(3):183-91. PubMed PMID: 14960030.
6: Saraggi D, Galuppini F, Fanelli GN, Remo A, Urso EDL, Bao RQ, Bacchin D, Guzzardo V, Luchini C, Braconi C, Farinati F, Rugge M, Fassan M. MiR-21 up-regulation in ampullary adenocarcinoma and its pre-invasive lesions. Pathol Res Pract. 2018 Jun;214(6):835-839. doi: 10.1016/j.prp.2018.04.018. Epub 2018 May 1. PubMed PMID: 29731265.