Roxibolone | CAS#60023-92-9 | androstane derivative

MedKoo Cat#: 461435 | Name: Roxibolone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Roxibolone is a androstane derivative.

Chemical Structure

Roxibolone

CAS#60023-92-9

Theoretical Analysis

MedKoo Cat#: 461435

Name: Roxibolone

CAS#: 60023-92-9

Chemical Formula: C21H28O5

Exact Mass: 360.1937

Molecular Weight: 360.45

Elemental Analysis: C, 69.98; H, 7.83; O, 22.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Roxibolone; Roxibolonum;

IUPAC/Chemical Name

(8S,9S,10R,11S,13S,14S,17S)-11,17-dihydroxy-10,13,17-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-2-carboxylic acid

InChi Key

JOFBZBDWOWPUMO-QARKFJNLSA-N

InChi Code

InChI=1S/C21H28O5/c1-19-9-13(18(24)25)15(22)8-11(19)4-5-12-14-6-7-21(3,26)20(14,2)10-16(23)17(12)19/h8-9,12,14,16-17,23,26H,4-7,10H2,1-3H3,(H,24,25)/t12-,14-,16-,17+,19-,20-,21-/m0/s1

SMILES Code

C[C@@]12[C@@](C)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C(C(O)=O)=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 360.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Berti F, Frova C, Colonna G. Androstane derivatives--roxibolone and decylroxibolone--devoid of any affinity for the androgenic prostate and muscle receptors. Arzneimittelforschung. 1986 Sep;36(9):1372-4. PubMed PMID: 3790189. 2: Felippone F, Resnati G, Scolastico C, Tronconi G. Synthesis of 2-carboxy-11 beta, 17 beta-dihydroxy-17-methyl-1, 4-androstadien-3-one and related compounds. Steroids. 1984 Mar;43(3):271-82. PubMed PMID: 6523544. 3: Berti F, Frova C, Colonna G, Galimberti E. Activity of a new androstane derivative on the nitrogen metabolism: antiglucocorticoid effects. Boll Chim Farm. 1985 Nov;124(11):469-76. PubMed PMID: 3833263.