Bendiocarb | CAS#22781-23-3 | insecticide

MedKoo Cat#: 461428 | Name: Bendiocarb

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bendiocarb is a carbamate insecticide and is one of the 12 insecticides recommended by the World Health Organization for use in malaria control in Africa.

Chemical Structure

Bendiocarb

CAS#22781-23-3

Theoretical Analysis

MedKoo Cat#: 461428

Name: Bendiocarb

CAS#: 22781-23-3

Chemical Formula: C11H13NO4

Exact Mass: 223.0845

Molecular Weight: 223.22

Elemental Analysis: C, 59.19; H, 5.87; N, 6.27; O, 28.67

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 350.00	2 weeks

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Related CAS #

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Synonym

Bendiocarb; Bencarbate; Dycarb; Ficam; Garvox; Multamat; Seedox; Turcam; NC 6897; NC6897; NC-6897; Niomil

IUPAC/Chemical Name

2,2-dimethylbenzo[d][1,3]dioxol-4-yl methylcarbamate

InChi Key

XEGGRYVFLWGFHI-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13)

SMILES Code

CC1(C)OC2=CC=CC(OC(NC)=O)=C2O1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

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Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 223.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Antonio-Nkondjio C, Poupardin R, Tene BF, Kopya E, Costantini C, Awono-Ambene P, Wondji CS. Investigation of mechanisms of bendiocarb resistance in Anopheles gambiae populations from the city of Yaoundé, Cameroon. Malar J. 2016 Aug 22;15(1):424. doi: 10.1186/s12936-016-1483-3. PubMed PMID: 27549778; PubMed Central PMCID: PMC4994282. 2: Yeebiyo Y, Dengela D, Tesfaye AG, Anshebo GY, Kolyada L, Wirtz R, Chibsa S, Fornadel C, George K, Belemvire A, Taffese HS, Lucas B. Short persistence of bendiocarb sprayed on pervious walls and its implication for the indoor residual spray program in Ethiopia. Parasit Vectors. 2016 May 5;9:266. doi: 10.1186/s13071-016-1549-7. PubMed PMID: 27151229; PubMed Central PMCID: PMC4858853. 3: Salehi A, Vatandoost H, Hazratian T, Sanei-Dehkordi A, Hooshyar H, Arbabi M, Salim-Abadi Y, Sharafati-Chaleshtori R, Gorouhi MA, Paksa A. Detection of Bendiocarb and Carbaryl Resistance Mechanisms among German Cockroach Blattella germanica (Blattaria: Blattellidae) Collected from Tabriz Hospitals, East Azerbaijan Province, Iran in 2013. J Arthropod Borne Dis. 2016 Jan 6;10(3):403-12. eCollection 2016 Sep. PubMed PMID: 27308298; PubMed Central PMCID: PMC4906746. 4: Petrovova E, Purzyc H, Mazensky D, Luptakova L, Torma N, Sopoliga I, Sedmera D. Morphometric alterations, steatosis, fibrosis and active caspase-3 detection in carbamate bendiocarb treated rabbit liver. Environ Toxicol. 2015 Feb;30(2):212-22. doi: 10.1002/tox.21887. Epub 2013 Jul 9. PubMed PMID: 23836410. 5: Randriamaherijaona S, Nepomichene T, Assoukpa J, Madec Y, Boyer S. First evaluation of bendiocarb in experimental huts using different substrates in Madagascar. Malar J. 2016 May 26;15(1):293. doi: 10.1186/s12936-016-1345-z. PubMed PMID: 27230626; PubMed Central PMCID: PMC4882781. 6: Bradley J, Hergott D, Garcia G, Lines J, Cook J, Slotman MA, Phiri WP, Schwabe C, Kleinschmidt I. A cluster randomized trial comparing deltamethrin and bendiocarb as insecticides for indoor residual spraying to control malaria on Bioko Island, Equatorial Guinea. Malar J. 2016 Jul 22;15(1):378. doi: 10.1186/s12936-016-1433-0. PubMed PMID: 27448667; PubMed Central PMCID: PMC4957409. 7: Thawer NG, Ngondi JM, Mugalura FE, Emmanuel I, Mwalimu CD, Morou E, Vontas J, Protopopoff N, Rowland M, Mutagahywa J, Lalji S, Molteni F, Ramsan MM, Willilo R, Wright A, Kafuko JM, Ndong I, Reithinger R, Magesa SM. Use of insecticide quantification kits to investigate the quality of spraying and decay rate of bendiocarb on different wall surfaces in Kagera region, Tanzania. Parasit Vectors. 2015 Apr 22;8:242. doi: 10.1186/s13071-015-0859-5. PubMed PMID: 25896604; PubMed Central PMCID: PMC4424830. 8: Holovska K, Almasiova V, Cigankova V. Ultrastructural changes in the rabbit liver induced by carbamate insecticide bendiocarb. J Environ Sci Health B. 2014;49(8):616-23. doi: 10.1080/03601234.2014.911593. PubMed PMID: 24901965. 9: Djènontin A, Aïmihouè O, Sèzonlin M, Damien GB, Ossè R, Soukou B, Padonou G, Chandre F, Akogbéto M. The residual life of bendiocarb on different substrates under laboratory and field conditions in Benin, Western Africa. BMC Res Notes. 2013 Nov 13;6:458. doi: 10.1186/1756-0500-6-458. PubMed PMID: 24220151; PubMed Central PMCID: PMC3831871. 10: Aïkpon R, Agossa F, Ossè R, Oussou O, Aïzoun N, Oké-Agbo F, Akogbéto M. Bendiocarb resistance in Anopheles gambiae s.l. populations from Atacora department in Benin, West Africa: a threat for malaria vector control. Parasit Vectors. 2013 Jun 26;6:192. doi: 10.1186/1756-3305-6-192. PubMed PMID: 23803527; PubMed Central PMCID: PMC3698110. 11: Agossa FR, Aïkpon R, Azondékon R, Govoetchan R, Padonnou GG, Oussou O, Oké-Agbo F, Akogbéto MC. Efficacy of various insecticides recommended for indoor residual spraying: pirimiphos methyl, potential alternative to bendiocarb for pyrethroid resistance management in Benin, West Africa. Trans R Soc Trop Med Hyg. 2014 Feb;108(2):84-91. doi: 10.1093/trstmh/trt117. PubMed PMID: 24463582. 12: Krockova J, Massányi P, Toman R, Danko J, Roychoudhury S. In vivo and in vitro effect of bendiocarb on rabbit testicular structure and spermatozoa motility. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2012;47(9):1301-11. doi: 10.1080/10934529.2012.672136. PubMed PMID: 22540655. 13: Petrovova E, Sedmera D, Luptakova L, Mazensky D, Danko J. Chick development and high dose of bendiocarb. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2012;47(9):1312-8. doi: 10.1080/10934529.2012.672138. PubMed PMID: 22540656. 14: Aïzoun N, Aïkpon R, Padonou GG, Oussou O, Oké-Agbo F, Gnanguenon V, Ossè R, Akogbéto M. Mixed-function oxidases and esterases associated with permethrin, deltamethrin and bendiocarb resistance in Anopheles gambiae s.l. in the south-north transect Benin, West Africa. Parasit Vectors. 2013 Aug 6;6:223. doi: 10.1186/1756-3305-6-223. PubMed PMID: 23919515; PubMed Central PMCID: PMC3750545. 15: Khodadoust S, Ghaedi M, Hadjmohammadi MR. Dispersive nano solid material-ultrasound assisted microextraction as a novel method for extraction and determination of bendiocarb and promecarb: response surface methodology. Talanta. 2013 Nov 15;116:637-46. doi: 10.1016/j.talanta.2013.07.013. Epub 2013 Jul 27. PubMed PMID: 24148456. 16: Polláková J, Kovalkovičová N, Csank T, Pistl J, Kočišová A, Legáth J. Evaluation of bendiocarb cytotoxicity in mammalian and insect cell cultures. J Environ Sci Health B. 2012;47(6):538-43. doi: 10.1080/03601234.2012.665671. PubMed PMID: 22494377. 17: Aïzoun N, Azondekon R, Aïkpon R, Gnanguenon V, Osse R, Asidi A, Akogbéto M. Study of the efficacy of a Wheaton coated bottle with permethrin and deltamethrin in laboratory conditions and a WHO impregnated paper with bendiocarb in field conditions. Asian Pac J Trop Biomed. 2014 Jun;4(6):492-7. doi: 10.12980/APJTB.4.2014C1111. PubMed PMID: 25182952; PubMed Central PMCID: PMC3994360. 18: Petrovová E, Mazenský D, Vdoviaková K, Massanyi P, Luptáková L, Smrco P. Effect of bendiocarb on development of the chick embryo. J Appl Toxicol. 2010 Jul;30(5):397-401. doi: 10.1002/jat.1509. PubMed PMID: 20127737. 19: Akogbéto MC, Padonou GG, Gbénou D, Irish S, Yadouleton A. Bendiocarb, a potential alternative against pyrethroid resistant Anopheles gambiae in Benin, West Africa. Malar J. 2010 Jul 14;9:204. doi: 10.1186/1475-2875-9-204. PubMed PMID: 20630056; PubMed Central PMCID: PMC2912925. 20: Protopopoff N, Matowo J, Malima R, Kavishe R, Kaaya R, Wright A, West PA, Kleinschmidt I, Kisinza W, Mosha FW, Rowland M. High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north-western Tanzania. Malar J. 2013 May 2;12:149. doi: 10.1186/1475-2875-12-149. PubMed PMID: 23638757; PubMed Central PMCID: PMC3655935.