IUPAC/Chemical Name
(3E,5E,7E,9E,11E,14S,16R,18R,20R,24S,26R,36S)-14,16,18,20,24,26-hexahydroxy-36-isopropyl-3-methyloxacyclohexatriaconta-3,5,7,9,11-pentaene-2,22,28-trione
InChi Key
YHVUXVJMFMUNKX-AFJHTLGSSA-N
InChi Code
InChI=1S/C39H62O10/c1-28(2)38-20-16-12-8-11-15-19-31(41)22-33(43)24-35(45)26-37(47)27-36(46)25-34(44)23-32(42)21-30(40)18-14-10-7-5-4-6-9-13-17-29(3)39(48)49-38/h4-7,9-10,13-14,17,28,30,32-36,38,40,42-46H,8,11-12,15-16,18-27H2,1-3H3/b6-4+,7-5+,13-9+,14-10+,29-17+/t30-,32+,33-,34+,35-,36+,38-/m0/s1
SMILES Code
O=C1C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](C/C=C/C=C/C=C/C=C/C=C(C(O[C@H](C(C)C)CCCCCCCC(C[C@H](O)C[C@H](O)C1)=O)=O)\C)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
690.91
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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8: Nikitina ET, Kazakova GG. [Antibiotic production of a proactinomycete variant of the roseofungin-producing organism]. Antibiotiki. 1972 Feb;17(2):114-7. Russian. PubMed PMID: 4554077.
9: Aĭtkhozhina NA. [Preparation and characteristics of protoplasts from various strains of Streptomyces roseoflavus var. roseofungini]. Antibiot Khimioter. 1992 Aug;37(8):22-4. Russian. PubMed PMID: 1456818.
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14: Shneĭder MA, Komarov EV, Travkin OV, Shtil'bans EB, Rachkovskaia LA. [Inactivation characteristics of polyene macrolide antibiotics]. Antibiot Med Biotekhnol. 1986 Oct;31(10):752-6. Russian. PubMed PMID: 3024559.
15: Vetlugina LA, Adiiatova ZhF, Khozhamuratova SSh, Rymzhanova ZA, Trenozhnikova LP, Kopytina MN. [Isolation of Actinomycetales from the soil of Kazakhstan on selective media with antibiotics]. Antibiot Khimioter. 1990 Feb;35(2):3-5. Russian. PubMed PMID: 2140036.
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