Rosellichalasin | CAS#123452-64-2 | metabolite

MedKoo Cat#: 461419 | Name: Rosellichalasin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Rosellichalasin is a metabolite produced by Rosellinia necatrix.

Chemical Structure

Rosellichalasin

CAS#123452-64-2

Theoretical Analysis

MedKoo Cat#: 461419

Name: Rosellichalasin

CAS#: 123452-64-2

Chemical Formula: C28H33NO5

Exact Mass: 463.2359

Molecular Weight: 463.57

Elemental Analysis: C, 72.55; H, 7.18; N, 3.02; O, 17.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Rosellichalasin;

IUPAC/Chemical Name

(1E,4S,6E,10aS,13S,13aS,14S,14aR,15aS,15bS)-13-benzyl-4,6,14,14a-tetramethyl-3,12,13,13a,14,14a,15a,15b-octahydro-5H-[1]oxacyclododecino[2,3-d]oxireno[2,3-f]isoindole-5,9,11(4H,8H)-trione

InChi Key

XNIXILZHFOBLTQ-RDTBASBDSA-N

InChi Code

InChI=1S/C28H33NO5/c1-16-9-8-12-20-25-27(4,34-25)18(3)23-21(15-19-10-6-5-7-11-19)29-26(32)28(20,23)33-22(30)14-13-17(2)24(16)31/h5-8,10-13,16,18,20-21,23,25H,9,14-15H2,1-4H3,(H,29,32)/b12-8+,17-13+/t16-,18-,20-,21-,23-,25-,27+,28+/m0/s1

SMILES Code

O=C(/C(C)=C/C1)[C@@H](C)C/C=C/[C@]2([H])[C@]3(OC1=O)C(N[C@@H](CC4=CC=CC=C4)[C@]3([H])[C@H](C)[C@]5(C)[C@@]2([H])O5)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 463.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Xiao L, Liu H, Wu N, Liu M, Wei J, Zhang Y, Lin X. Characterization of the high cytochalasin E and rosellichalasin producing-Aspergillus sp. nov. F1 isolated from marine solar saltern in China. World J Microbiol Biotechnol. 2013 Jan;29(1):11-7. doi: 10.1007/s11274-012-1152-9. Epub 2012 Aug 22. PubMed PMID: 22910972. 2: Yu L, Ding W, Ma Z. Induced production of cytochalasans in co-culture of marine fungus Aspergillus flavipes and actinomycete Streptomyces sp. Nat Prod Res. 2016 Aug;30(15):1718-23. doi: 10.1080/14786419.2015.1136910. Epub 2016 Jan 19. PubMed PMID: 26783945. 3: Zhang HW, Zhang J, Hu S, Zhang ZJ, Zhu CJ, Ng SW, Tan RX. Ardeemins and cytochalasins from Aspergillus terreus residing in Artemisia annua. Planta Med. 2010 Oct;76(14):1616-21. doi: 10.1055/s-0030-1249781. Epub 2010 Apr 9. PubMed PMID: 20383815. 4: Barrow CJ, Sedlock DM, Sun HH, Cooper R, Gillum AM. WIN 66306, a new neurokinin antagonist produced by an Aspergillus species: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo). 1994 Nov;47(11):1182-7. PubMed PMID: 7528191.