Synonym
Furildioxime; alpha-Furil dioxime; (Z,Z)-a-Furil Dioxime;
IUPAC/Chemical Name
1,2-Ethanedione, 1,2-di-2-furanyl-, 1,2-dioxime
InChi Key
RBOZTFPIXJBLPK-WGDLNXRISA-N
InChi Code
InChI=1S/C10H8N2O4/c13-11-9(7-3-1-5-15-7)10(12-14)8-4-2-6-16-8/h1-6,13-14H/b11-9+,12-10+
SMILES Code
O/N=C(C1=CC=CO1)/C(C2=CC=CO2)=N/O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
220.18
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Memon N, Memon S, Solangi AR, Soomro R, Soomro R. Single-channel flow injection spectrophotometric determination of nickel using furildioxime in micellar solution. ScientificWorldJournal. 2012;2012:418047. doi: 10.1100/2012/418047. Epub 2012 May 1. PubMed PMID: 22654605; PubMed Central PMCID: PMC3361272.
2: Rahnama R, Jojadeh ZC, Jamali MR. Spectrophotometric determination of trace levels of nickel in water samples after dispersive liquid liquid microextraction using 2,2'-furildioxime as the complexing agent. Acta Chim Slov. 2012 Sep;59(3):641-7. PubMed PMID: 24061321.
3: Bissett DL, McBride JF. Synergistic topical photoprotection by a combination of the iron chelator 2-furildioxime and sunscreen. J Am Acad Dermatol. 1996 Oct;35(4):546-9. PubMed PMID: 8859281.
4: Rahnama Kozani R, Mofid-Nakhaei J, Jamali MR. Rapid spectrophotometric determination of trace amounts of palladium in water samples after dispersive liquid-liquid microextraction. Environ Monit Assess. 2013 Aug;185(8):6531-7. doi: 10.1007/s10661-012-3044-8. Epub 2012 Dec 16. PubMed PMID: 23242461.
5: Rahnama R, Najafi M. The use of rapidly synergistic cloud point extraction for the separation and preconcentration of trace amounts of Ni (II) ions from food and water samples coupling with flame atomic absorption spectrometry determination. Environ Monit Assess. 2016 Mar;188(3):150. doi: 10.1007/s10661-016-5146-1. Epub 2016 Feb 9. PubMed PMID: 26857255.
6: Mikac-Dević D, Sunderman FW Jr, Nomoto S. Furildioxime method for nickel analysis in serum and urine by electrothermal atomic absorption spectrometry. Clin Chem. 1977 Jun;23(6):948-56. PubMed PMID: 858204.
7: Satake M, Matsumura Y, Fujinaga T. Spectrophotometric determination of nickel after separation by adsorption of its alpha-furildioxime complex on naphthalene. Talanta. 1978 November - December;25(11-12):718-20. PubMed PMID: 18962360.
8: Bissett DL, Oelrich DM, Hannon DP. Evaluation of a topical iron chelator in animals and in human beings: short-term photoprotection by 2-furildioxime. J Am Acad Dermatol. 1994 Oct;31(4):572-8. PubMed PMID: 8089282.
9: Saçmacı S, Kartal S. Determination of palladium by on-line flow-injection direct spectrophotometry in environmental samples using 2,2'-furyldioxime as a chelator. Talanta. 2013 May 15;109:26-30. doi: 10.1016/j.talanta.2013.03.030. Epub 2013 Mar 21. PubMed PMID: 23618137.
10: Debal E, Peynot S, Poliakoff O, Revault M. [Not Available]. Talanta. 1979 Apr;26(4):267-72. French. PubMed PMID: 18962429.
11: Jordanov N, Pavlova M, Stefanov S. A new catalytic reaction of rhenium and its analytical application. Talanta. 1978 Jul;25(7):389-93. PubMed PMID: 18962281.
12: Solanke KR, Khopkar SM. Rapid extraction and spectrophotometric determination of vanadium(IV) with thiothenoyltrifluoroacetone. Talanta. 1974 Mar;21(3):245-8. PubMed PMID: 18961448.
13: Mitani H, Koshiishi I, Sumita T, Imanari T. Prevention of the photodamage in the hairless mouse dorsal skin by kojic acid as an iron chelator. Eur J Pharmacol. 2001 Jan 5;411(1-2):169-174. PubMed PMID: 11137872.
