Platenolide I | CAS#52212-94-9 | macrolactone

MedKoo Cat#: 598671 | Name: Platenolide I

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Platenolide I is a macrolactone isolated from Streptomyces platensis.

Chemical Structure

Platenolide I

CAS#52212-94-9

Theoretical Analysis

MedKoo Cat#: 598671

Name: Platenolide I

CAS#: 52212-94-9

Chemical Formula: C20H32O6

Exact Mass: 368.2199

Molecular Weight: 368.47

Elemental Analysis: C, 65.19; H, 8.75; O, 26.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Platenolide I;

IUPAC/Chemical Name

(11E,13E)-7-ethyl-4,6-dihydroxy-5-methoxy-9,16-dimethyloxacyclohexadeca-11,13-diene-2,10-dione

InChi Key

VWVDRJWACDDRKD-LQPGMRSMSA-N

InChi Code

InChI=1S/C20H32O6/c1-5-15-11-13(2)16(21)10-8-6-7-9-14(3)26-18(23)12-17(22)20(25-4)19(15)24/h6-8,10,13-15,17,19-20,22,24H,5,9,11-12H2,1-4H3/b7-6+,10-8+

SMILES Code

O=C(CC(O)C(OC)C(O)C(CC)CC1C)OC(C)C/C=C/C=C/C1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 368.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nguyen HC, Darbon E, Thai R, Pernodet JL, Lautru S. Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens. Antimicrob Agents Chemother. 2013 Aug;57(8):3836-42. doi: 10.1128/AAC.00512-13. Epub 2013 May 28. PubMed PMID: 23716060; PubMed Central PMCID: PMC3719765. 2: Gräfe U, Schade W, Ihn W, Reinhardt G, Dornberger K, Thrum H, Radics L. Isolation and structures of nitrogen-free platenolide glycosides. I. The 5-O-(deoxy-3'-C-acetyl-beta-D-hexopyranosyl)-platenolides I and II. J Antibiot (Tokyo). 1980 Jun;33(6):566-73. PubMed PMID: 7419470. 3: Gräfe U, Schade W, Ihn W, Reinhardt G, Dornberger K, Thrum H, Radics L. Isolation and structures of nitrogen-free platenolide glycosides. II. The 5-O-(alpha-mycarosyl)- and 5-O-(3'-demethyl-beta-mycaroxyl)-platenolides I and II. J Antibiot (Tokyo). 1980 Jun;33(6):574-8. PubMed PMID: 7419471. 4: Kuhstoss S, Huber M, Turner JR, Paschal JW, Rao RN. Production of a novel polyketide through the construction of a hybrid polyketide synthase. Gene. 1996 Dec 12;183(1-2):231-6. PubMed PMID: 8996112. 5: Gräfe U, Fleck WF, Schade W, Reinhardt G, Tresselt D, Thrum H. The platenolides I and II as precursors of turimycin. J Antibiot (Tokyo). 1980 Jun;33(6):663-4. PubMed PMID: 7419477.