Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 µg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 µg/ml, respectively) and S. faecalis (MIC = 0.8 µg/ml).
MedKoo Cat#: 598658
Name: Leucomycin a5
CAS#: 18361-45-0
Chemical Formula: C39H65NO14
Exact Mass: 771.4405
Molecular Weight: 771.94
Elemental Analysis: C, 60.68; H, 8.49; N, 1.81; O, 29.02
The following data is based on the product molecular weight 771.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
