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MedKoo Cat#: 598641 | Name: Leucinostatin D

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Leucinostatin D is a novel peptide antibiotic from Paecilomyces marquandii.

Chemical Structure

Leucinostatin D
Leucinostatin D
CAS#100334-47-2

Theoretical Analysis

MedKoo Cat#: 598641

Name: Leucinostatin D

CAS#: 100334-47-2

Chemical Formula: C56H101N11O11

Exact Mass: 1103.7682

Molecular Weight: 1104.49

Elemental Analysis: C, 60.90; H, 9.22; N, 13.95; O, 15.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Leucinostatin D; Leucinostatin-D;
IUPAC/Chemical Name
(4R)-N-(26-(1-hydroxy-2-methylpropyl)-17,20-diisobutyl-4,11,11,14,14,23,23,31-octamethyl-6,10,13,16,19,22,25,28-octaoxo-2,5,9,12,15,18,21,24,27-nonaazadotriacontan-29-yl)-4-methyl-1-((S,E)-4-methylhex-2-enoyl)pyrrolidine-2-carboxamide
InChi Key
RDUJTYZLXJPVKP-YDZNBPEVSA-N
InChi Code
InChI=1S/C56H101N11O11/c1-20-35(10)21-22-43(69)67-30-36(11)28-41(67)49(74)61-38(25-31(2)3)47(72)63-44(45(70)34(8)9)50(75)65-55(15,16)52(77)62-39(26-32(4)5)46(71)60-40(27-33(6)7)48(73)64-56(17,18)53(78)66-54(13,14)51(76)58-24-23-42(68)59-37(12)29-57-19/h21-22,31-41,44-45,57,70H,20,23-30H2,1-19H3,(H,58,76)(H,59,68)(H,60,71)(H,61,74)(H,62,77)(H,63,72)(H,64,73)(H,65,75)(H,66,78)/b22-21+/t35-,36+,37?,38?,39?,40?,41?,44?,45?/m0/s1
SMILES Code
CC[C@@H](/C=C/C(N1C[C@H](C)CC1C(NC(C(NC(C(NC(C)(C(NC(C(NC(C(NC(C)(C(NC(C)(C(NCCC(NC(CNC)C)=O)=O)C)=O)C)=O)CC(C)C)=O)CC(C)C)=O)C)=O)C(O)C(C)C)=O)CC(C)C)=O)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,104.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rossi C, Tuttobello L, Ricci M, Casinovi CG, Radics L. Leucinostatin D, a novel peptide antibiotic from Paecilomyces marquandii. J Antibiot (Tokyo). 1987 Jan;40(1):130-3. PubMed PMID: 3558114. 2: Martinez AF, Moraes LA. Liquid chromatography-tandem mass spectrometry characterization of five new leucinostatins produced by Paecilomyces lilacinus CG-189. J Antibiot (Tokyo). 2015 Mar;68(3):178-84. doi: 10.1038/ja.2014.120. Epub 2014 Sep 3. PubMed PMID: 25182486. 3: Mikami Y, Yazawa K, Fukushima K, Arai T, Udagawa S, Samson RA. Paecilotoxin production in clinical or terrestrial isolates of Paecilomyces lilacinus strains. Mycopathologia. 1989 Dec;108(3):195-9. PubMed PMID: 2615806.