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MedKoo Cat#: 592621 | Name: Nafimidone alcohol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nafimidone alcohol is a Nafimidone metabolite.

Chemical Structure

Nafimidone alcohol
Nafimidone alcohol
CAS#71009-17-1

Theoretical Analysis

MedKoo Cat#: 592621

Name: Nafimidone alcohol

CAS#: 71009-17-1

Chemical Formula: C15H14N2O

Exact Mass: 238.1106

Molecular Weight: 238.29

Elemental Analysis: C, 75.61; H, 5.92; N, 11.76; O, 6.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Nafimidone alcohol
IUPAC/Chemical Name
1H-Imidazole-1-ethanol, alpha-2-naphthalenyl-
InChi Key
LFAPKHXSAABGPQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14N2O/c18-15(10-17-8-7-16-11-17)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11,15,18H,10H2
SMILES Code
OC(C1=CC=C2C=CC=CC2=C1)CN3C=CN=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 238.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gunawan S, Treiman DM. High-performance liquid chromatographic determination of nafimidone and its major metabolite nafimidone alcohol in human plasma and urine. J Chromatogr. 1987 Mar 6;414(2):389-98. PubMed PMID: 3571406. 2: Rush WR, Smith SA, Mulvey JH, Graham DJ, Chaplin MD. Inhibition and induction of hepatic drug metabolism in rats and mice by nafimidone and its major metabolite nafimidone alcohol. Drug Metab Dispos. 1987 Jul-Aug;15(4):571-8. PubMed PMID: 2888633. 3: Graham DJ, Hama KM, Smith SA, Kurz L, Chaplin MD, Hall DJ. Disposition of nafimidone in rats. Drug Metab Dispos. 1987 Jul-Aug;15(4):565-70. PubMed PMID: 2888632. 4: Karakurt A, Ozalp M, Işik S, Stables JP, Dalkara S. Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. Bioorg Med Chem. 2010 Apr 15;18(8):2902-11. doi: 10.1016/j.bmc.2010.03.010. Epub 2010 Mar 9. PubMed PMID: 20363141. 5: Treiman DM, Gunawan S. Pharmacokinetics of nafimidone in patients with chronic intractable epilepsy. Clin Pharmacokinet. 1987 Jun;12(6):433-9. PubMed PMID: 3608344. 6: Rush WR, Alexander OF, Hall DJ, Dow RJ, Tokes L, Kurz L, Graham DJ. The metabolism of nafimidone hydrochloride in the dog, primates and man. Xenobiotica. 1990 Jan;20(1):123-32. PubMed PMID: 2109431.