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MedKoo Cat#: 598561 | Name: Lemnalol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lemnalol is a natural marine compound isolated from the Formosan soft coral Lemnalia cervicorni. Lemnalol produced anti-inflammatory and analgesic effects in carrageenan-injected rats.

Chemical Structure

Lemnalol
Lemnalol
CAS#82570-34-1

Theoretical Analysis

MedKoo Cat#: 598561

Name: Lemnalol

CAS#: 82570-34-1

Chemical Formula: C15H24O

Exact Mass: 220.1827

Molecular Weight: 220.35

Elemental Analysis: C, 81.76; H, 10.98; O, 7.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lemnalol;
IUPAC/Chemical Name
(1R,2S,4R,6S,7R,8S)-8-isopropyl-1-methyl-3-methylenetricyclo[4.4.0.02,7]decan-4-ol
InChi Key
LPXOPRGPLUWGKB-JRULLXGZSA-N
InChi Code
InChI=1S/C15H24O/c1-8(2)10-5-6-15(4)11-7-12(16)9(3)14(15)13(10)11/h8,10-14,16H,3,5-7H2,1-2,4H3/t10-,11-,12+,13+,14-,15+/m0/s1
SMILES Code
C=C1[C@H](O)C[C@@H]2[C@@]3(C)CC[C@@H](C(C)C)[C@H]2[C@H]13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 220.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lee HP, Lin YY, Duh CY, Huang SY, Wang HM, Wu SF, Lin SC, Jean YH, Wen ZH. Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. J Pharm Pharmacol. 2015 Feb;67(2):274-85. doi: 10.1111/jphp.12331. Epub 2014 Dec 31. PubMed PMID: 25557511. 2: Lee HP, Huang SY, Lin YY, Wang HM, Jean YH, Wu SF, Duh CY, Wen ZH. Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. Mar Drugs. 2013 Jan 10;11(1):99-113. doi: 10.3390/md11010099. PubMed PMID: 23306170; PubMed Central PMCID: PMC3564160. 3: Lin YC, Huang SY, Jean YH, Chen WF, Sung CS, Kao ES, Wang HM, Chakraborty C, Duh CY, Wen ZH. Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats. Behav Pharmacol. 2011 Dec;22(8):739-50. doi: 10.1097/FBP.0b013e32834d0ecb. PubMed PMID: 22067479. 4: Jean YH, Chen WF, Duh CY, Huang SY, Hsu CH, Lin CS, Sung CS, Chen IM, Wen ZH. Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni. Eur J Pharmacol. 2008 Jan 14;578(2-3):323-31. Epub 2007 Sep 20. PubMed PMID: 17916350. 5: Kikuchi H, Manda T, Kobayashi K, Yamada Y, Iguchi K. Anti-tumor activity of lemnalol isolated from the soft coral Lemnalia tenuis Verseveldt. Chem Pharm Bull (Tokyo). 1983 Mar;31(3):1086-8. PubMed PMID: 6136342. 6: Cheng SY, Lin EH, Huang JS, Wen ZH, Duh CY. Ylangene-type and nardosinane-type sesquiterpenoids from the soft corals Lemnalia flava and Paralemnalia thyrsoides. Chem Pharm Bull (Tokyo). 2010 Mar;58(3):381-5. PubMed PMID: 20190445. 7: Duh CY, El-Gamal AA, Song PY, Wang SK, Dai CF. Steroids and sesquiterpenoids from the soft corals Dendronephthya gigantea and Lemnalia cervicorni. J Nat Prod. 2004 Oct;67(10):1650-3. PubMed PMID: 15497934.