MedKoo Cat#: 598556 | Name: LEK 8804

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LEK 8804 is a 5-HT(1A) receptor agonist and 5-HT(2) receptor antagonist.

Chemical Structure

LEK 8804
LEK 8804
CAS#153415-44-2

Theoretical Analysis

MedKoo Cat#: 598556

Name: LEK 8804

CAS#: 153415-44-2

Chemical Formula: C19H19N3O

Exact Mass: 305.1528

Molecular Weight: 305.38

Elemental Analysis: C, 74.73; H, 6.27; N, 13.76; O, 5.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LEK 8804; LEK-8804; LEK8804;
IUPAC/Chemical Name
(6aR,9R)-7-methyl-N-(prop-2-yn-1-yl)-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
InChi Key
WZTGESDWBWZMSE-CXAGYDPISA-N
InChi Code
InChI=1S/C19H19N3O/c1-3-7-20-19(23)13-8-15-14-5-4-6-16-18(14)12(10-21-16)9-17(15)22(2)11-13/h1,4-6,8,10,13,17,21H,7,9,11H2,2H3,(H,20,23)/t13-,17-/m1/s1
SMILES Code
[H][C@@]1(N(C)C[C@H](C(NCC#C)=O)C=C12)CC3=CNC4=C3C2=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 305.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Krisch I, Bole-Vunduk B. Behavioral studies on LEK-8804, a new ergoline derivative with potent 5-HT1A receptor agonist and 5-HT2 receptor antagonist activity. Pharmacol Biochem Behav. 1994 Feb;47(2):301-5. PubMed PMID: 8146221. 2: Kleven MS, Assié MB, Koek W. Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats. J Pharmacol Exp Ther. 1997 Aug;282(2):747-59. PubMed PMID: 9262338.