Iprobenfos | CAS#26087-47-8 | organophosphorus pesticide

MedKoo Cat#: 461319 | Name: Iprobenfos

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iprobenfos (IBP) is an organophosphorus pesticide.

Chemical Structure

Iprobenfos

CAS#26087-47-8

Theoretical Analysis

MedKoo Cat#: 461319

Name: Iprobenfos

CAS#: 26087-47-8

Chemical Formula: C13H21O3PS

Exact Mass: 288.0949

Molecular Weight: 288.34

Elemental Analysis: C, 54.15; H, 7.34; O, 16.65; P, 10.74; S, 11.12

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 385.00	2 Weeks

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Related CAS #

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Synonym

Iprobenfos; Kitazin L; Kitazin P; Ricid P; Ricid II;

IUPAC/Chemical Name

S-benzyl O,O-diisopropyl phosphorothioate

InChi Key

FCOAHACKGGIURQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C13H21O3PS/c1-11(2)15-17(14,16-12(3)4)18-10-13-8-6-5-7-9-13/h5-9,11-12H,10H2,1-4H3

SMILES Code

O=P(OC(C)C)(SCC1=CC=CC=C1)OC(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos is also a choline biosynthesis inhibitor.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 288.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Kwon YS, Nguyen VT, Park JG, Gu MB. Detection of iprobenfos and edifenphos using a new multi-aptasensor. Anal Chim Acta. 2015 Apr 8;868:60-6. doi: 10.1016/j.aca.2015.02.020. Epub 2015 Feb 12. PubMed PMID: 25813235. 2: Tao LM, Yang JZ, Zhuang PJ, Tang ZH. Effect of a mixture of iprobenfos and malathion on the development of malathion resistance in the mosquito Culex pipiens pallens Coq. Pest Manag Sci. 2006 Jan;62(1):86-90. PubMed PMID: 16235270. 3: Jung JH, Addison RF, Shim WJ. Characterization of cholinesterases in marbled sole, Limanda yokohamae, and their inhibition in vitro by the fungicide iprobenfos. Mar Environ Res. 2007 Jun;63(5):471-8. Epub 2007 Jan 4. PubMed PMID: 17300836. 4: Añasco NC, Koyama J, Uno S. Pesticide residues in coastal waters affected by rice paddy effluents temporarily stored in a wastewater reservoir in southern Japan. Arch Environ Contam Toxicol. 2010 Feb;58(2):352-60. doi: 10.1007/s00244-009-9364-1. Epub 2009 Jul 17. PubMed PMID: 19609592. 5: Tsuda T, Igawa T, Tanaka K, Hirota D. Changes of concentrations, shipment amounts and ecological risk of pesticides in river water flowing into Lake Biwa. Bull Environ Contam Toxicol. 2011 Sep;87(3):307-11. doi: 10.1007/s00128-011-0335-7. Epub 2011 Jun 15. PubMed PMID: 21674152. 6: Cho HR, Park JS, Kim J, Han SB, Choi YS. Multiresidue method for the quantitation of 20 pesticides in aquatic products. Anal Bioanal Chem. 2015 Dec;407(30):9043-52. doi: 10.1007/s00216-015-9071-x. Epub 2015 Oct 14. PubMed PMID: 26466578. 7: Woo S, Yum S, Kim DW, Park HS. Transcripts level responses in a marine medaka (Oryzias javanicus) exposed to organophosphorus pesticide. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):427-32. doi: 10.1016/j.cbpc.2008.10.100. Epub 2008 Nov 1. PubMed PMID: 18983944. 8: Chen S, Han Q, Wang X, Yang M, Zhang Z, Li P, Chen A, Hu C, Li S. IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway. Cell Death Dis. 2013 Oct 10;4:e842. doi: 10.1038/cddis.2013.380. PubMed PMID: 24113176; PubMed Central PMCID: PMC3824689. 9: Kim MS, Kim GW, Park TJ. A facile and sensitive detection of organophosphorus chemicals by rapid aggregation of gold nanoparticles using organic compounds. Biosens Bioelectron. 2015 May 15;67:408-12. doi: 10.1016/j.bios.2014.08.073. Epub 2014 Sep 3. PubMed PMID: 25216978. 10: Kim S, Park SY, Kim H, Kim D, Lee SW, Kim HT, Lee JH, Choi W. Isolation and Characterization of the Colletotrichum acutatum ABC Transporter CaABC1. Plant Pathol J. 2014 Dec;30(4):375-83. doi: 10.5423/PPJ.OA.08.2014.0077. Epub 2014 Dec 15. PubMed PMID: 25506302; PubMed Central PMCID: PMC4262290. 11: Tawata S, Taira S, Kobamoto N, Zhu J, Ishihara M, Toyama S. Synthesis and antifungal activity of cinnamic acid esters. Biosci Biotechnol Biochem. 1996 May;60(5):909-10. PubMed PMID: 8704323. 12: Fujikawa M, Nakao K, Shimizu R, Akamatsu M. The usefulness of an artificial membrane accumulation index for estimation of the bioconcentration factor of organophosphorus pesticides. Chemosphere. 2009 Feb;74(6):751-7. doi: 10.1016/j.chemosphere.2008.10.046. Epub 2008 Dec 11. PubMed PMID: 19084258. 13: Nohara S, Iwakuma T. Residual pesticides and their toxicity to freshwater shrimp in the littoral and pelagic zones of Lake Kasumigaura, Japan. Chemosphere. 1996 Oct;33(7):1417-24. PubMed PMID: 8799998. 14: Choi JY, Yu J, Yang DB, Ra K, Kim KT, Hong GH, Shin KH. Acetylthiocholine (ATC)--cleaving cholinesterase (ChE) activity as a potential biomarker of pesticide exposure in the Manila clam, Ruditapes philippinarum, of Korea. Mar Environ Res. 2011 Apr;71(3):162-8. doi: 10.1016/j.marenvres.2010.12.007. Epub 2011 Jan 5. PubMed PMID: 21262527. 15: Riza LV, Gzhegotskiĭ MI. [Hygienic evaluation of working conditions during the conduct of aviation-chemical activities with ricid-II in agriculture]. Gig Sanit. 1987 Feb;(2):85-6. Russian. PubMed PMID: 3569972. 16: Min KJ, Cha CG, Popendorf W. Determination of urinary metabolites of phosalone, methidathion, and IBP after oral administration and dermal application to rats. Bull Environ Contam Toxicol. 2005 May;74(5):809-16. PubMed PMID: 16097311. 17: Maeda M, Tanaka Y, Doi O, Nakano A, Nishijima M, Akamatsu Y. Two types of inhibitor of phospholipid methylation in MOPC-31C cells with modified membrane phospholipids. Biochim Biophys Acta. 1981 Nov 23;666(2):275-83. PubMed PMID: 7306566. 18: Tawata S, Taira S, Kikizu H, Kobamoto N, Ishihara M, Toyama S. Synthesis and Fungicidal Activity of 6-Alkyl Six-membered Cyclic Thiophosphates. Biosci Biotechnol Biochem. 1997 Jan;61(12):2103-5. doi: 10.1271/bbb.61.2103. PubMed PMID: 27396887. 19: Riza LV, Semenova GS, Kordonets IG. [Toxic action of ricid-II on the eye]. Gig Tr Prof Zabol. 1985 Mar;(3):50-2. Russian. PubMed PMID: 4007572. 20: Chura DA, Manenko AK, Drobiazko VP. [Toxicokinetics of ricid-P in the bodies of warm-blooded animals]. Gig Tr Prof Zabol. 1986 Nov;(11):53-4. Russian. PubMed PMID: 3803972.