Phtstllap | CAS#59131-98-5 | hormone-releasing factor

MedKoo Cat#: 598520 | Name: Phtstllap

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phtstllap is a luteinizing hormone-releasing factor

Chemical Structure

Phtstllap

CAS#59131-98-5

Theoretical Analysis

MedKoo Cat#: 598520

Name: Phtstllap

CAS#: 59131-98-5

Chemical Formula: C59H83N17O13

Exact Mass: 1237.6356

Molecular Weight: 1238.41

Elemental Analysis: C, 57.22; H, 6.76; N, 19.23; O, 16.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

LHRH, lys(6)-N-Et-pronh2(9)-; Ldgpe-lhfshrh; Phtstllap;

IUPAC/Chemical Name

(S)-N-acetyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-L-lysyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide

InChi Key

DTDOTHCVEWUJMA-UILVTTEASA-N

InChi Code

InChI=1S/C59H83N17O13/c1-32(2)24-43(52(83)70-42(13-8-22-64-59(61)62)58(89)76-23-9-14-48(76)57(88)67-33(3)78)71-50(81)40(12-6-7-21-60)69-53(84)44(25-34-15-17-37(79)18-16-34)72-56(87)47(30-77)75-54(85)45(26-35-28-65-39-11-5-4-10-38(35)39)73-55(86)46(27-36-29-63-31-66-36)74-51(82)41-19-20-49(80)68-41/h4-5,10-11,15-18,28-29,31-32,40-48,65,77,79H,6-9,12-14,19-27,30,60H2,1-3H3,(H,63,66)(H,68,80)(H,69,84)(H,70,83)(H,71,81)(H,72,87)(H,73,86)(H,74,82)(H,75,85)(H4,61,62,64)(H,67,78,88)/t40-,41-,42-,43-,44-,45-,46-,47-,48-/m0/s1

SMILES Code

CC(NC([C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CO)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CNC=N5)NC([C@H](CC6)NC6=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,238.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Conn PM, Hazum E. Luteinizing hormone release and gonadotropin-releasing hormone (GnRH) receptor internalization: independent actions of GnRH. Endocrinology. 1981 Dec;109(6):2040-5. PubMed PMID: 6273126. 2: Wynn PC, Suarez-Quian CA, Childs GV, Catt KJ. Pituitary binding and internalization of radioiodinated gonadotropin-releasing hormone agonist and antagonist ligands in vitro and in vivo. Endocrinology. 1986 Oct;119(4):1852-63. PubMed PMID: 3530725. 3: Janovick JA, Haviv F, Fitzpatrick TD, Conn PM. Differential orientation of a GnRH agonist and antagonist in the pituitary GnRH receptor. Endocrinology. 1993 Aug;133(2):942-5. PubMed PMID: 8393780.