LD 490 | CAS#58336-35-9 | laser dye

MedKoo Cat#: 598518 | Name: LD 490

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

LD 490 is a laser dye.

Chemical Structure

LD 490

CAS#58336-35-9

Theoretical Analysis

MedKoo Cat#: 598518

Name: LD 490

CAS#: 58336-35-9

Chemical Formula: C15H15NO2

Exact Mass: 241.1103

Molecular Weight: 241.29

Elemental Analysis: C, 74.67; H, 6.27; N, 5.81; O, 13.26

Price and Availability

Size	Price	Availability	Quantity
200mg	USD 350.00	2 Weeks
1g	USD 750.00	2 Weeks

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Synonym

LD 490; LD-490; LD490; C 6H; C-6H; C6H; Exciton LD 490;

IUPAC/Chemical Name

2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one

InChi Key

MZSOXGPKUOAXNY-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H15NO2/c17-13-6-5-11-9-10-3-1-7-16-8-2-4-12(14(10)16)15(11)18-13/h5-6,9H,1-4,7-8H2

SMILES Code

O=C1C=CC2=CC3=C4N(CCC3)CCCC4=C2O1

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

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Product Data

Product Data

Instruction

View handling instruction

Biological target:

Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye.

In vitro activity:

A triaxial flashlamp-pumped dye laser has been used to perform laser damage testing of metal surfaces in the blue-green spectral region. Using LD490 laser dye, the laser produces 0.18-J, 0.5-microsec pulses at 492 nm. Reference: Appl Opt. 1982 Nov 15;21(22):4063-6. https://pubmed.ncbi.nlm.nih.gov/20401009/

In vivo activity:

Herein, based on the combined effect of two different fluorescence quenching groups, this study rationally developed a novel fluorescent probe for hypochlorite with extremely low background fluorescence. Moreover, the fluorescence imaging different concentration of hypochlorite in zebrafish has been successfully conducted. Reference: Anal Biochem. 2020 Aug 1;602:113795. https://pubmed.ncbi.nlm.nih.gov/32473120/

Preparing Stock Solutions

The following data is based on the product molecular weight 241.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

1. Usta HM, Forough M, Persil Çetinkol Ö. Coumarin 6H-fused fluorescent probe for highly sensitive detection of coralyne using oligonucleotide-modified silver nanoparticles. Anal Bioanal Chem. 2022 Oct;414(24):7299-7313. doi: 10.1007/s00216-022-04282-2. Epub 2022 Aug 17. PMID: 35976422. 2. Marrs CD, Faith WN, Dancy JH, Porteus JO. Pulsed laser-induced damage of metals at 492 nm. Appl Opt. 1982 Nov 15;21(22):4063-6. doi: 10.1364/AO.21.004063. PMID: 20401009. 3. Han Z, Dong L, Sun F, Long L, Jiang S, Dai X, Zhang M. A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish. Anal Biochem. 2020 Aug 1;602:113795. doi: 10.1016/j.ab.2020.113795. Epub 2020 May 28. PMID: 32473120.

In vitro protocol:

In vivo protocol:

1. Han Z, Dong L, Sun F, Long L, Jiang S, Dai X, Zhang M. A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish. Anal Biochem. 2020 Aug 1;602:113795. doi: 10.1016/j.ab.2020.113795. Epub 2020 May 28. PMID: 32473120.

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