MedKoo Cat#: 598515 | Name: Pipebuzone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pipebuzone is an anti-inflammatory agent. Pipebuzone was used for the treatment of various rheumatic diseases. It was particularly well tolerated, clinically and pathologically, and had a reliable anti inflammatory action.

Chemical Structure

Pipebuzone
Pipebuzone
CAS#27315-91-9

Theoretical Analysis

MedKoo Cat#: 598515

Name: Pipebuzone

CAS#: 27315-91-9

Chemical Formula: C25H32N4O2

Exact Mass: 420.2525

Molecular Weight: 420.55

Elemental Analysis: C, 71.40; H, 7.67; N, 13.32; O, 7.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Pipebuzone; Pipebuzonum; LD 4644; LD-4644; LD4644;
IUPAC/Chemical Name
4-butyl-4-((4-methylpiperazin-1-yl)methyl)-1,2-diphenylpyrazolidine-3,5-dione
InChi Key
XGNKHIPCARGLGS-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H32N4O2/c1-3-4-15-25(20-27-18-16-26(2)17-19-27)23(30)28(21-11-7-5-8-12-21)29(24(25)31)22-13-9-6-10-14-22/h5-14H,3-4,15-20H2,1-2H3
SMILES Code
O=C(C1(CCCC)CN2CCN(C)CC2)N(C3=CC=CC=C3)N(C4=CC=CC=C4)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 420.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Goguel S. [Use of pipebuzone in odonto-stomatology and maxillo-facial surgery (apropos of 51 cases)]. Chir Dent Fr. 1976 Jun 2;46(307):63-8. French. PubMed PMID: 1076140. 2: Clerc-Aldige. [Protection of the pulp in a conjoined prosthesis by using anti-inflammatory agent pipebuzone]. Rev Odontostomatol (Paris). 1975 Nov-Dec;4(6):481-8. French. PubMed PMID: 1062837.