MedKoo Cat#: 461282 | Name: RH 160

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RH 160 is a special lipid-soluble dye.

Chemical Structure

RH 160
RH 160
CAS#83668-92-2

Theoretical Analysis

MedKoo Cat#: 461282

Name: RH 160

CAS#: 83668-92-2

Chemical Formula: C27H38N2O3S

Exact Mass: 470.2603

Molecular Weight: 470.67

Elemental Analysis: C, 68.90; H, 8.14; N, 5.95; O, 10.20; S, 6.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
RH 160; RH-160; RH160;
IUPAC/Chemical Name
4-(4-((1E,3E)-4-(4-(dibutylamino)phenyl)buta-1,3-dien-1-yl)pyridin-1-ium-1-yl)butane-1-sulfonate
InChi Key
AGTMTHJNRMNTDK-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H38N2O3S/c1-3-5-20-29(21-6-4-2)27-15-13-25(14-16-27)11-7-8-12-26-17-22-28(23-18-26)19-9-10-24-33(30,31)32/h7-8,11-18,22-23H,3-6,9-10,19-21,24H2,1-2H3
SMILES Code
O=S(CCCC[N+]1=CC=C(/C=C/C=C/C2=CC=C(N(CCCC)CCCC)C=C2)C=C1)([O-])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 470.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Malkov DY, Sokolov VS. Fluorescent styryl dyes of the RH series affect a potential drop on the membrane/solution boundary. Biochim Biophys Acta. 1996 Jan 31;1278(2):197-204. PubMed PMID: 8593277. 2: Ostroumova OS, Efimova SS, Schagina LV. Probing amphotericin B single channel activity by membrane dipole modifiers. PLoS One. 2012;7(1):e30261. doi: 10.1371/journal.pone.0030261. Epub 2012 Jan 19. PubMed PMID: 22276169; PubMed Central PMCID: PMC3261894. 3: Malkov DY, Pavlov KV, Sokolov VS. Dipole potential drop due to RH-dye adsorption on the lipid bilayer and its influence on Na+/K+-ATPase activity. Ann N Y Acad Sci. 1997 Nov 3;834:357-60. PubMed PMID: 9432911. 4: Crowe WE, Leader JP. Resistive properties of the epithelial membranes of the urinary bladder of the toad, Bufo marinus, determined using the fluorescent dye, RH160. Pflugers Arch. 1994 Jun;427(3-4):210-8. PubMed PMID: 8072838.