IUPAC/Chemical Name
(3bR,8bS)-2,3b,4,5,7,8b,9,10-octahydroindazolo[7,6-g]indazole
InChi Key
RTMZVYUACSCNRL-AOOOYVTPSA-N
InChi Code
InChI=1S/C12H14N4/c1-3-9-10(11-7(1)5-13-15-11)4-2-8-6-14-16-12(8)9/h5-6,9-10H,1-4H2,(H,13,15)(H,14,16)/t9-,10+
SMILES Code
[H][C@]12CCC3=CNN=C3[C@]1([H])CCC4=CNN=C42
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
214.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Hurtado I, Urbina C, Suárez C, Beyer B, Magro AM. Preparation and evaluation of a soluble derivative of the antiallergic compound trans-2, 3b, 4, 5, 7, 8b, 9, 10-octahydronaphtho [1, 2-c:5, 6-c'] dipyrazole (LC-6). Int J Immunopharmacol. 1985;7(5):635-8. PubMed PMID: 2864322.
2: Magro AM, Hurtado I. The orally active antiallergic compound, LC-6 (trans-2,3b,4,5,7,8b,9,10-octahydronaphtho[1,2-c:5,6-C] dipyrazole) inhibits the arachidonate lipoxygenase enzyme. J Immunopharmacol. 1983;5(3):191-202. PubMed PMID: 6197487.
3: Hurtado I, Urbina C. LC-6 inhibition of the rat skin reactions is due to mediator release inhibitor and not to mediator antagonism. Acta Cient Venez. 1983;34(1):44-7. PubMed PMID: 6424369.
