MedKoo Cat#: 592579 | Name: Ethylnorepinephrine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ethylnorepinephrine hydrochloride is a unique bronchodilator.

Chemical Structure

 Ethylnorepinephrine hydrochloride
Ethylnorepinephrine hydrochloride
CAS#3198-07-0

Theoretical Analysis

MedKoo Cat#: 592579

Name: Ethylnorepinephrine hydrochloride

CAS#: 3198-07-0

Chemical Formula: C10H16ClNO3

Exact Mass: 233.0819

Molecular Weight: 233.69

Elemental Analysis: C, 51.40; H, 6.90; Cl, 15.17; N, 5.99; O, 20.54

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Synonym
Ethylnorepinephrine hydrochloride; Bronkephrine; Butanefrine hydrochloride
IUPAC/Chemical Name
1,2-Benzenediol, 4-(2-amino-1-hydroxybutyl)-, hydrochloride
InChi Key
NZDMRJGAFPUTMZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H15NO3.ClH/c1-2-7(11)10(14)6-3-4-8(12)9(13)5-6;/h3-5,7,10,12-14H,2,11H2,1H3;1H
SMILES Code
OC1=CC=C(C(O)C(N)CC)C=C1O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 233.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: CHRISTENSEN JM, VALASEK FE, TAINTER ML. Ethylnorepinephrine; a unique bronchodilator. Am Pract Dig Treat. 1958 Jun;9(6):916-21. PubMed PMID: 13533786. 2: LANDS AM, LUDUENA FP, GRANT JI, ANANENKO E. The pharmacologic action of some analogs of 1-(3,4-dihydroxyphenyl)-2-amino-1-butanol (ethylnorepinephrine). J Pharmacol Exp Ther. 1950 May;99(1):45-56. PubMed PMID: 15429016. 3: KORNEL L. A case of calcified ventricular aneurysm with progressive heart block; observations on the effect of ethylnorepinephrine. Cardiologia. 1958;32(2):101-9. PubMed PMID: 13500349. 4: Besse JC, Furchgott RF. Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta. J Pharmacol Exp Ther. 1976 Apr;197(1):66-78. PubMed PMID: 4613. 5: LEVY L 2nd, SEABURY JH. Spirometric evaluation of ethyl-nor-epinephrine in bronchial asthma. J Allergy. 1948 Jan;19(1):58-61. PubMed PMID: 18917406. 6: HARTMAN MM. Ethyl-nor-epinephrine by inhalation for bronchial asthma; a comparison with epinephrine. J Allergy. 1946 Mar;17:106-11. PubMed PMID: 21020002. 7: BUBERT HM, DOENGES JP. Ethyl-norepinephrine, a new drug for symptomatic relief of bronchial asthma. Bull Sch Med Univ Md. 1946 Jul;31:12-20. PubMed PMID: 20994333.