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MedKoo Cat#: 592574 | Name: Butoxamine HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Butoxamine hydrochloride is a beta-2 selective adrenergic antagonist. It is used primarily in animal and tissue experiments to characterize beta-2 receptor involvement and identify beta-2 receptors..

Chemical Structure

Butoxamine HCl
Butoxamine HCl
CAS#5696-15-1

Theoretical Analysis

MedKoo Cat#: 592574

Name: Butoxamine HCl

CAS#: 5696-15-1

Chemical Formula: C15H26ClNO3

Exact Mass: 0.0000

Molecular Weight: 303.83

Elemental Analysis: C, 59.30; H, 8.63; Cl, 11.67; N, 4.61; O, 15.80

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
Butoxamine hydrochloride; Butoxamine HCl; NSC 106565; NSC-106565; NSC106565
IUPAC/Chemical Name
alpha-(1-(tert-Butylamino)ethyl)-2,5-dimethoxybenzyl alcohol hydrochloride
InChi Key
URPAECSKKQLCII-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H
SMILES Code
COC1=CC=C(OC)C(C(O)C(NC(C)(C)C)C)=C1.[H]Cl
Appearance
Solid powder
Purity
>95% (mixture of diastereomers)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 303.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PLoS One. 2014 Apr 14;9(4):e94726. doi: 10.1371/journal.pone.0094726. eCollection 2014. PubMed PMID: 24733123; PubMed Central PMCID: PMC3986230. 13: Peng XY, Huang Y, Wang XL, Cao LF, Chen LH, Luo WF, Liu T. Adrenergic β2-receptor mediates itch hypersensitivity following heterotypic chronic stress in rats. Neuroreport. 2015 Dec 2;26(17):1003-10. doi: 10.1097/WNR.0000000000000458. PubMed PMID: 26426856. 14: Zhang Y, Guan Z, Reader B, Shawler T, Mandrekar-Colucci S, Huang K, Weil Z, Bratasz A, Wells J, Powell ND, Sheridan JF, Whitacre CC, Rabchevsky AG, Nash MS, Popovich PG. Autonomic dysreflexia causes chronic immune suppression after spinal cord injury. J Neurosci. 2013 Aug 7;33(32):12970-81. doi: 10.1523/JNEUROSCI.1974-13.2013. PubMed PMID: 23926252; PubMed Central PMCID: PMC3735880. 15: Zlotnik A, Klin Y, Gruenbaum BF, Gruenbaum SE, Ohayon S, Boyko M, Sheiner E, Aricha-Tamir B, Shapira Y, Teichberg VI. The activation of β2-adrenergic receptors in naïve rats causes a reduction of blood glutamate levels: relevance to stress and neuroprotection. Neurochem Res. 2011 May;36(5):732-8. doi: 10.1007/s11064-010-0388-8. Epub 2011 Jan 5. PubMed PMID: 21207137. 16: Gilbert EF, Bruyere HJ Jr, Ishikawa S, Cheung MO, Hodach RJ. The effect of practolol and butoxamine on aortic arch malformation in beta adrenoreceptor stimulated chick embryos. Teratology. 1977 Jun;15(3):317-23. PubMed PMID: 196355. 17: Sugarman A, Kahn T. Calcium channel blockers enhance extrarenal potassium disposal in the rat. Am J Physiol. 1986 Apr;250(4 Pt 2):F695-701. PubMed PMID: 3083698. 18: Goldman JM, Hadley ME. The effect of butoxamine, N-isopropylmethoxamine and salbutamol (AH-3365) on melanophore beta-adrenergic receptors. J Pharm Pharmacol. 1969 Dec;21(12):854-5. PubMed PMID: 4391059. 19: Kamio N, Suzuki T, Watanabe Y, Suhara Y, Osakabe N. 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