MedKoo Cat#: 592566 | Name: Butidrine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Butidrine has an Antiarrhythmic effect.

Chemical Structure

Butidrine
Butidrine
CAS#7433-10-5

Theoretical Analysis

MedKoo Cat#: 592566

Name: Butidrine

CAS#: 7433-10-5

Chemical Formula: C16H25NO

Exact Mass: 247.1936

Molecular Weight: 247.38

Elemental Analysis: C, 77.68; H, 10.19; N, 5.66; O, 6.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Butidrine
IUPAC/Chemical Name
alpha-((sec-Butylamino)methyl)-5,6,7,8-tetrahydro-2-naphthalene-methanol
InChi Key
GVNYSERWAKVROD-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H25NO/c1-3-12(2)17-11-16(18)15-9-8-13-6-4-5-7-14(13)10-15/h8-10,12,16-18H,3-7,11H2,1-2H3
SMILES Code
OC(CNC(C)CC)C1=CC=C2CCCCC2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 247.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bonomi L, Perfetti S, Noya E, Bellucci R, Massa F. Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Mar 5;210(1):1-8. PubMed PMID: 35031. 2: Truelove JF, van Petten GR, Willes RF. Action of several -adrenoceptor blocking drugs in the pregnant sheep and foetus. Br J Pharmacol. 1973 Jan;47(1):161-71. PubMed PMID: 4146153; PubMed Central PMCID: PMC1776527. 3: Musso E, Taccardi B. [Modifications of the electric activity of the guinea pig myocardial fiber induced by 4 stereoisomers of butidrine, a new compound with adrenergic beta receptor blockading action]. Arch Int Pharmacodyn Ther. 1970 Jan;183(1):173-89. Italian. PubMed PMID: 4392359. 4: Rossano C, Romoli M, Brunozzi LT, Monti GB, Pavoni P. [Antiarrhythmic effect of butidrine: experimental study on arrhythmias induced by N-adrenaline in halothane anesthesia]. Acta Anaesthesiol. 1969 Jul-Aug;20(4):663-700. Italian. PubMed PMID: 4397385. 5: Barbi G, Tallone B. The effect of a new beta blocking drug (butidrine) on some biohumoral indices, liver and kidney function and exercise tolerance. Panminerva Med. 1969 Jul-Aug;11(7):372-7. PubMed PMID: 4390702. 6: Di Renzi L, Cassone R, Leggio F, Lucisano V. [Variations of the velocity of the rheographic wave induced by butidrine administered during intravenous infusion of adrenaline in normal subjects]. Boll Soc Ital Cardiol. 1969;14(2):158-68. Italian. PubMed PMID: 4933738. 7: Ferrini R, Miragoli G, Croce G. [The pharmacological actions of butidrine. A comparative study of this new beta-adrenergic receptor antagonist and its four stereoisomers]. Arzneimittelforschung. 1968 Jul;18(7):829-33. PubMed PMID: 4387812. 8: Visioli O, Botti G, Tagliavini S, Chizzola A. [Clinico-pharmacological study on the cardiodynamic interaction between digitalis and the adrenergic beta blockader butidrine]. Clin Ter. 1968 May 15;45(3):231-48. Italian. PubMed PMID: 4390650. 9: Bertaccini G, Impicciatore M, Visioli O, Malagnino G. Inotropic and chronotropic effects of two stereoisomers of butidrine, a new adrenergic beta-blocking agent, on isolated rabbit heart and rat auricles. Farmaco Sci. 1968 Mar;23(3):183-96. PubMed PMID: 5713108. 10: Di Renzi L, Cassone R, Lucisano V, Leggio F. [Changes in the systolic phases of left ventricle mechanics induced by the administration of butidrine during slow intravenous infusion of adrenaline in normal subjects]. Boll Soc Ital Cardiol. 1968;13(4):443-59. Italian. PubMed PMID: 4895505. 11: Ferrini R. Some pharmacological properties of four stereoisomers of butidrine, a new adrenergic beta-receptor antagonist. Arzneimittelforschung. 1968 Jan;18(1):48-50. PubMed PMID: 4386975. 12: Pasqualucci V, Calderazzo AB, Pucciarini LG, Vecchiarelli G. [Experimental study on the use of butidrine in anesthesia]. Acta Anaesthesiol. 1967 Nov-Dec;18(6):785-99. Italian. PubMed PMID: 5633200. 13: Dal Palu C, Viterbo B, Gasparotto G. [Changes in cardiac activity and pressure values following to acute endocranice compression in animals treated with butidrine]. Minerva Cardioangiol. 1967 Mar;15(5):332-6. Italian. PubMed PMID: 5603838. 14: Visioli O, Dallavalle L, Bianchi G, Botti G, Malagnino G. [Effects of the association of potassium and a beta-adrenergic blocking agent (butidrine) on normal cardiac rhythm and on experimental arrhythmias caused by adrenaline and aconitine in the rabbit]. Minerva Cardioangiol. 1966 Oct;14(10):613-4. Italian. PubMed PMID: 5996321.