Bisoxatin acetate | CAS#14008-48-1 | laxative

MedKoo Cat#: 598488 | Name: Bisoxatin acetate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bisoxatin acetate is a contact laxative in pearl form.

Chemical Structure

Bisoxatin acetate

CAS#14008-48-1

Theoretical Analysis

MedKoo Cat#: 598488

Name: Bisoxatin acetate

CAS#: 14008-48-1

Chemical Formula: C24H19NO6

Exact Mass: 417.1212

Molecular Weight: 417.41

Elemental Analysis: C, 69.06; H, 4.59; N, 3.36; O, 23.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Bisoxatin acetate; Kritel Tropfen; WY 8138; WY-8138; WY8138; Exodol; Talsis; Maratan;

IUPAC/Chemical Name

(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2,2-diyl)bis(4,1-phenylene) diacetate

InChi Key

ZCBJDQBSLZREAA-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H19NO6/c1-15(26)29-19-11-7-17(8-12-19)24(18-9-13-20(14-10-18)30-16(2)27)23(28)25-21-5-3-4-6-22(21)31-24/h3-14H,1-2H3,(H,25,28)

SMILES Code

O=C1C(C2=CC=C(OC(C)=O)C=C2)(C3=CC=C(OC(C)=O)C=C3)OC4=CC=CC=C4N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 417.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rider JA. Treatment of acute and chronic constipation with bisoxatin acetate and bisacodyl. Double-blind crossover study. Curr Ther Res Clin Exp. 1971 Jun;13(6):386-92. PubMed PMID: 4996225. 2: de Lima de Mon M, Cioccia AM, González E, Hevia P. [Effects of secretory and osmotic diarrhea on rats intestinal function and morphology]. Arch Latinoam Nutr. 2002 Mar;52(1):20-8. Spanish. PubMed PMID: 12214542. 3: Mattivi G, Scoz R, Donner C. [Treatment of chronic constipation with a contact laxative in pearl form: bisoxatin acetate]. Atti Accad Med Lomb. 1972;27(1-4):127-33. Italian. PubMed PMID: 4681351. 4: de Wolff FA, de Haas EJ, Verweij M. A screening method for establishing laxative abuse. Clin Chem. 1981 Jun;27(6):914-7. PubMed PMID: 6894566.