Synonym
Fenazaflor; Fenoflurazole; Tarzol; Lovozal; NC 5016; NC-5016; NC5016; NSC 191025; NSC-191025; NSC191025;
IUPAC/Chemical Name
phenyl 5,6-dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole-1-carboxylate
InChi Key
ISVQSVPUDBVFFU-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H7Cl2F3N2O2/c16-9-6-11-12(7-10(9)17)22(13(21-11)15(18,19)20)14(23)24-8-4-2-1-3-5-8/h1-7H
SMILES Code
O=C(N1C2=CC(Cl)=C(Cl)C=C2N=C1C(F)(F)F)OC3=CC=CC=C3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
375.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bowker DW, Casida JE. Metabolism of the acaricide chemical, fenazaflor(5,6-dichloro-1-phenoxycarbonyl-2-trifluoromethylbenzimidazole) in certain mammals, insects, and plants. J Agric Food Chem. 1969 Sep;17(5):956-66. doi: 10.1021/jf60165a043. PubMed PMID: 21428329.
2: Weetman DF, Cain K, Sweetman AJ. The mechanism of the myocardial depression produced by congeners of the acaricide, fenazaflor. Arch Int Pharmacodyn Ther. 1973 Jun;203(2):342-7. PubMed PMID: 4270276.
3: Astashkin EN, Khodorova AB, Surin AM, Diachenko VI, Kolomiets AF, Fokin AV. [Effect of inhibitors of lipoxygenase oxidation of arachidonic acid and phenofluorazole on rat thymocyte cytoplasmic pH and on the change of this parameter induced by concanavalin A]. Dokl Akad Nauk SSSR. 1992;325(4):869-73. Russian. PubMed PMID: 8593766.
4: Astashkin EI, Surin AM, Khodorova AB, Nikolaeva IS, Diachenko VI, Kolomiets AF, Fokin AV. [Study of the effect of phenophtorazole on the calcium ion concentration in rat thymocyte cytoplasm and on changes of this parameter, induced by concanavalin A]. Dokl Akad Nauk SSSR. 1991;317(2):499-502. Russian. PubMed PMID: 1769314.
