Dodecyl maltoside | CAS#69227-93-6 | surfactant

MedKoo Cat#: 598466 | Name: Dodecyl maltoside

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dodecyl maltoside is a surfactant.

Chemical Structure

Dodecyl maltoside

CAS#69227-93-6

Theoretical Analysis

MedKoo Cat#: 598466

Name: Dodecyl maltoside

CAS#: 69227-93-6

Chemical Formula: C24H46O11

Exact Mass: 510.3040

Molecular Weight: 510.62

Elemental Analysis: C, 56.45; H, 9.08; O, 34.47

Price and Availability

Size	Price	Availability
100mg	USD 90.00	Ready to ship
250mg	USD 150.00	Ready to ship
500mg	USD 250.00	Ready to ship
1g	USD 450.00	Ready to ship
2g	USD 750.00	Ready to ship

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Related CAS #

No Data

Synonym

n-DODECYL-beta-D-Maltoside; Dodecyl maltoside; Dodecyl-beta-D-maltoside; Lauryl maltoside; DDM; Lauryl-β-D-maltoside

IUPAC/Chemical Name

(2R,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6R)-6-(dodecyloxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

InChi Key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

InChi Code

InChI=1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

SMILES Code

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)O)[C@@H]1OCCCCCCCCCCCC

Appearance

Solid powder

Purity

>97% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Certificate of Analysis

View CoA: current batch, Lot#A25M05B28

Safety Data Sheet (SDS)

View Safety Data Sheet (SDS)

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 510.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Haji Abdolvahab M, Fazeli A, Fazeli MR, Brinks V, Schellekens H. The effects of dodecyl maltoside and sodium dodecyl sulfate surfactants on the stability and aggregation of recombinant interferon Beta-1b. J Interferon Cytokine Res. 2014 Nov;34(11):894-901. doi: 10.1089/jir.2013.0131. Epub 2014 Jun 23. PubMed PMID: 24956236. 2: Xu L, Matsunaga F, Xi J, Li M, Ma J, Liu R. n-Dodecyl β-D-maltoside specifically competes with general anesthetics for anesthetic binding sites. J Biomol Struct Dyn. 2014;32(11):1833-40. doi: 10.1080/07391102.2013.838699. Epub 2013 Sep 24. PubMed PMID: 24063524. 3: Fegyver E, Mészáros R. Complexation between Sodium Poly(styrenesulfonate) and Alkyltrimethylammonium Bromides in the Presence of Dodecyl Maltoside. J Phys Chem B. 2015 Apr 23;119(16):5336-46. doi: 10.1021/acs.jpcb.5b01206. Epub 2015 Apr 8. PubMed PMID: 25807451. 4: Boos J, Preisig N, Stubenrauch C. Dilational surface rheology studies of n-dodecyl-β-D-maltoside, hexaoxyethylene dodecyl ether, and their 1:1 mixture. Adv Colloid Interface Sci. 2013 Sep;197-198:108-17. doi: 10.1016/j.cis.2013.05.001. Epub 2013 May 9. Review. PubMed PMID: 23726302. 5: Hiruma-Shimizu K, Kalverda AP, Henderson PJ, Homans SW, Patching SG. Synthesis of uniformly deuterated n-dodecyl-β-D-maltoside (d39-DDM) for solubilization of membrane proteins in TROSY NMR experiments. J Labelled Comp Radiopharm. 2014 Dec;57(14):737-43. doi: 10.1002/jlcr.3249. Epub 2014 Dec 9. PubMed PMID: 25491565. 6: Rouse SL, Marcoux J, Robinson CV, Sansom MS. Dodecyl maltoside protects membrane proteins in vacuo. Biophys J. 2013 Aug 6;105(3):648-56. doi: 10.1016/j.bpj.2013.06.025. PubMed PMID: 23931313; PubMed Central PMCID: PMC3736684. 7: Liu J, Wang F, Mao J, Zhang Z, Liu Z, Huang G, Cheng K, Zou H. High-sensitivity N-glycoproteomic analysis of mouse brain tissue by protein extraction with a mild detergent of N-dodecyl β-D-maltoside. Anal Chem. 2015 Feb 17;87(4):2054-7. doi: 10.1021/ac504700t. Epub 2015 Feb 5. PubMed PMID: 25646822. 8: Panagakou I, Touloupakis E, Ghanotakis DF. Structural characterization of hydroperoxide lyase in dodecyl maltoside by using circular dichroism. Protein J. 2013 Jan;32(1):1-6. doi: 10.1007/s10930-012-9454-1. PubMed PMID: 23076732. 9: Ali MS, Al-Lohedan HA. Biophysical characterization of the interaction between human serum albumin and n-dodecyl β-D-maltoside: A multi-technique approach. Colloids Surf B Biointerfaces. 2015 Oct 1;134:392-400. doi: 10.1016/j.colsurfb.2015.06.062. Epub 2015 Jul 4. PubMed PMID: 26218712. 10: Abel S, Lorieau A, de Foresta B, Dupradeau FY, Marchi M. Bindings of hMRP1 transmembrane peptides with dodecylphosphocholine and dodecyl-β-d-maltoside micelles: a molecular dynamics simulation study. Biochim Biophys Acta. 2014 Jan;1838(1 Pt B):493-509. doi: 10.1016/j.bbamem.2013.10.012. Epub 2013 Oct 21. PubMed PMID: 24157718. 11: Le RK, Harris BJ, Iwuchukwu IJ, Bruce BD, Cheng X, Qian S, Heller WT, O'Neill H, Frymier PD. Analysis of the solution structure of Thermosynechococcus elongatus photosystem I in n-dodecyl-β-D-maltoside using small-angle neutron scattering and molecular dynamics simulation. Arch Biochem Biophys. 2014 May 15;550-551:50-7. doi: 10.1016/j.abb.2014.04.005. Epub 2014 Apr 24. PubMed PMID: 24769336. 12: Feng S, Bummer PM. Competition of hydrophobic steroids with sodium dodecyl sulfate, dodecyltrimethylammonium bromide, or dodecyl β-D-maltoside for the dodecane/water interface. Langmuir. 2012 Dec 11;28(49):16927-32. doi: 10.1021/la303751e. Epub 2012 Nov 26. PubMed PMID: 23151278. 13: Patel SG, Bummer PM. Development of a Robust Method for Simultaneous Quantification of Polymer (HPMC) and Surfactant (Dodecyl β-D-Maltoside) in Nanosuspensions. AAPS PharmSciTech. 2016 Oct;17(5):1182-91. doi: 10.1208/s12249-015-0451-5. Epub 2015 Dec 3. PubMed PMID: 26634749. 14: Plazzotta B, Fegyver E, Mészáros R, Pedersen JS. Anisometric Polyelectrolyte/Mixed Surfactant Nanoassemblies Formed by the Association of Poly(diallyldimethylammonium chloride) with Sodium Dodecyl Sulfate and Dodecyl Maltoside. Langmuir. 2015 Jul 7;31(26):7242-50. doi: 10.1021/acs.langmuir.5b01280. Epub 2015 Jun 23. PubMed PMID: 26057578. 15: Abel S, Dupradeau FY, Raman EP, MacKerell AD Jr, Marchi M. Molecular simulations of dodecyl-β-maltoside micelles in water: influence of the headgroup conformation and force field parameters. J Phys Chem B. 2011 Jan 27;115(3):487-99. doi: 10.1021/jp109545v. Epub 2010 Dec 30. PubMed PMID: 21192681; PubMed Central PMCID: PMC3076730. 16: Phung D, Granum PE, Dietrich R, Märtlbauer E, Hardy SP. Inhibition of cytotoxicity by the Nhe cytotoxin of Bacillus cereus through the interaction of dodecyl maltoside with the NheB component. FEMS Microbiol Lett. 2012 May;330(2):98-104. doi: 10.1111/j.1574-6968.2012.02538.x. Epub 2012 Mar 22. PubMed PMID: 22385099. 17: Lambert O, Levy D, Ranck JL, Leblanc G, Rigaud JL. A new "gel-like" phase in dodecyl maltoside-lipid mixtures: implications in solubilization and reconstitution studies. Biophys J. 1998 Feb;74(2 Pt 1):918-30. PubMed PMID: 9533703; PubMed Central PMCID: PMC1302571. 18: Rifkin RA, Maggio ET, Dike S, Kerr DA, Levy M. n-Dodecyl-β-D-maltoside inhibits aggregation of human interferon-β-1b and reduces its immunogenicity. J Neuroimmune Pharmacol. 2011 Mar;6(1):158-62. doi: 10.1007/s11481-010-9226-7. Epub 2010 Jun 8. PubMed PMID: 20532646. 19: Bass WT, Bricker TM. Dodecyl maltoside-sodium dodecyl sulfate two-dimensional polyacrylamide gel electrophoresis of chloroplast thylakoid membrane proteins. Anal Biochem. 1988 Jun;171(2):330-8. PubMed PMID: 3407930. 20: Barera S, Pagliano C, Pape T, Saracco G, Barber J. Characterization of PSII-LHCII supercomplexes isolated from pea thylakoid membrane by one-step treatment with α- and β-dodecyl-D-maltoside. Philos Trans R Soc Lond B Biol Sci. 2012 Dec 19;367(1608):3389-99. doi: 10.1098/rstb.2012.0056. PubMed PMID: 23148265; PubMed Central PMCID: PMC3497064.