IUPAC/Chemical Name
A name could not be generated for this structure.
InChi Key
SYTUVFMLCUYKEL-BIEXLURBSA-N
InChi Code
InChI=1S/C46H56N2O14/c1-23-14-13-15-24(2)45(56)48-36-31(22-47-60-21-20-58-30-16-11-10-12-17-30)40(53)33-34(41(36)54)39(52)28(6)43-35(33)44(55)46(8,62-43)59-19-18-32(57-9)25(3)42(61-29(7)49)27(5)38(51)26(4)37(23)50/h10-19,22-23,25-27,32,37-38,42,50-54H,20-21H2,1-9H3,(H,48,56)/b14-13+,19-18+,24-15-,47-22+
SMILES Code
Cc1c(OC(O/C=C/C(OC)C(C)C(OC(C)=O)C(C)C(O)C(C)C(O)C(C)/C=C/C=C(C)\C(N2)=O)(C)C3=O)c3c4c(O)c(/C=N/OCCOc5ccccc5)c2c(O)c4c1O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
860.95
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Păunescu E. Reprimun--an antibiotic with large spectrum and immunomodulatory properties. Pneumoftiziologia. 1994 Jul-Dec;43(3-4):189-95. PubMed PMID: 7767104.
2: Păunescu E, Didilescu C, Mihălţan F, Udrea S, Serbescu A, Dănălache-Dumitrescu M, Smărăndache M, Stoinescu M, Zaharescu C, Petre A, et al. Advantages of treatment with Reprimun in sarcoidosis. Med Interne. 1989 Jul-Sep;27(3):225-8. PubMed PMID: 2617077.
3: Păunescu E. Why the treatment with Reprimun could be efficient for tuberculosis prevention in HIV infected individuals. Pneumoftiziologia. 1992 Jan-Mar;41(1):45-6. PubMed PMID: 1299399.
4: Păunescu E, Burnea D, Zaharescu C, Stoinescu M, Algeorge G, Petre A, Corlan E, Smărăndache M, Dănălache-Dumitrescu M, Jienescu Z, Oprişiu G. [Preliminary results of the use of a new derivative of rifamycin SV in the treatment of sarcoidosis]. Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1982 Apr-Jun;31(2):141-50. Romanian. PubMed PMID: 6294806.
5: Anastasatu C, Albu A, Burnea D, Didilescu C, Gîrlonţa V, Mihălţan P, Popescu N, Savu A, Udrea S, Păunescu E. [The advantages of Reprimum therapy in pulmonary sarcoidosis and other granulomatous diseases]. Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1989 Jul-Sep;38(3):259-64. Romanian. PubMed PMID: 2559463.
