MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 598416 | Name: Thiazolinobutazone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.

Chemical Structure

Thiazolinobutazone
Thiazolinobutazone
CAS#54749-86-9

Theoretical Analysis

MedKoo Cat#: 598416

Name: Thiazolinobutazone

CAS#: 54749-86-9

Chemical Formula: C22H26N4O2S

Exact Mass:

Molecular Weight: 410.53

Elemental Analysis: C, 64.37; H, 6.38; N, 13.65; O, 7.79; S, 7.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Thiazolinobutazone; LAS 11871; LAS-11871; LAS11871; TZB;
IUPAC/Chemical Name
4-butyl-1,2-diphenylpyrazolidine-3,5-dione compound with 4,5-dihydrothiazol-2-amine (1:1)
InChi Key
IMKNHLPRDSWAHW-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H20N2O2.C3H6N2S/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16;4-3-5-1-2-6-3/h4-13,17H,2-3,14H2,1H3;1-2H2,(H2,4,5)
SMILES Code
O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=CC=C3)C1=O.NC4=NCCS4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Colombo M, Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11 871). III. General pharmacology, ulcerogenic effects and acute toxicity. Arzneimittelforschung. 1976;26(7):1347-56. PubMed PMID: 1036923. 2: Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11871). I. Anti-inflammatory effects. Arzneimittelforschung. 1974 Nov;24(11):1786-9. PubMed PMID: 4480050. 3: Márquez M, Roberts DJ. Pharmacological properties of thiazolinobutazone (LAS 11871). II. Analgesic and antipyretic effects. Arzneimittelforschung. 1974 Nov;24(11):1790-2. PubMed PMID: 4480051. 4: Moragues J, Thiele K, Márquez M, Colombo M, Roberts DJ. The preparation and pharmacological selection of a new anti-inflammatory agent, thiazolinobutazone. Arzneimittelforschung. 1974 Nov;24(11):1785-6. PubMed PMID: 4480049. 5: Niki I. [Contribution of diabetic research to versatile strategies for the treatment of diabetes mellitus]. Nihon Yakurigaku Zasshi. 2003 Sep;122(3):228-35. Review. Japanese. PubMed PMID: 12939540.