Lantadene B | CAS#467-82-3 | active principle

MedKoo Cat#: 598379 | Name: Lantadene B

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lantadene B is an active principle of Lantana camara L.

Chemical Structure

Lantadene B

CAS#467-82-3

Theoretical Analysis

MedKoo Cat#: 598379

Name: Lantadene B

CAS#: 467-82-3

Chemical Formula: C35H52O5

Exact Mass: 552.3815

Molecular Weight: 552.79

Elemental Analysis: C, 76.05; H, 9.48; O, 14.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Lantadene B; HSDB 3504;

IUPAC/Chemical Name

(4R,4aS,6aS,6bR,8aR,12aR,12bR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-4-((3-methylbut-2-enoyl)oxy)-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid

InChi Key

VYPAPFHUHDWCBI-QQAPFUPGSA-N

InChi Code

InChI=1S/C35H52O5/c1-21(2)18-28(37)40-27-20-30(3,4)19-23-22-10-11-25-32(7)14-13-26(36)31(5,6)24(32)12-15-34(25,9)33(22,8)16-17-35(23,27)29(38)39/h10,18,23-25,27H,11-17,19-20H2,1-9H3,(H,38,39)/t23-,24-,25+,27+,32-,33+,34+,35-/m0/s1

SMILES Code

CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)C[C@@H](OC(/C=C(C)\C)=O)[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 552.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: LOUW PG. Lantadene A, the active principle of Lantana camara L.; isolation of lantadene B, and the oxygen functions of lantadene A and lantadene B. Onderstepoort J Vet Sci Anim Ind. 1948 Mar;23(1-2):233-8. PubMed PMID: 18863442. 2: Dong Y, Zhang M, Ling B. [Antifeeding effects of crude lantadene from Lantana camara on Plutella xylostella and Spodoptera litura larvae]. Ying Yong Sheng Tai Xue Bao. 2005 Dec;16(12):2361-4. Chinese. PubMed PMID: 16515188. 3: Tailor NK, Jaiswal V, Lan SS, Lee HB, Sharma M. Synthesis, selective cancer cytotoxicity and mechanistic studies of novel analogs of lantadenes. Anticancer Agents Med Chem. 2013 Jul 1;13(6):957-66. PubMed PMID: 23293887. 4: Tailor NK, Boon HL, Sharma M. Synthesis and in vitro anticancer studies of novel C-2 arylidene congeners of lantadenes. Eur J Med Chem. 2013 Jun;64:285-91. doi: 10.1016/j.ejmech.2013.04.009. Epub 2013 Apr 10. PubMed PMID: 23644211. 5: Sharma S, Sharma OP, Singh B, Bhat TK. Biotransformation of lantadenes, the pentacyclic triterpenoid hepatotoxins of lantana plant, in guinea pig. Toxicon. 2000 Sep;38(9):1191-202. PubMed PMID: 10736473. 6: Sharma OP, Dawra RK, Makkar HP. Toxicity of isolated Lantana (Lantana camara L) constituents to male and female guinea pigs. Vet Hum Toxicol. 1989 Feb;31(1):10-3. PubMed PMID: 2711601.