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MedKoo Cat#: 558491 | Name: Thioquinapiperifil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor. It was found in dietary supplements. LC-MS analysis indicated that the supplements contain two major compounds. One was identified as thiodenafil (synonym: thiosildenafil) by direct comparison with the authentic compound.

Chemical Structure

Thioquinapiperifil
Thioquinapiperifil
CAS#220060-39-9

Theoretical Analysis

MedKoo Cat#: 558491

Name: Thioquinapiperifil

CAS#: 220060-39-9

Chemical Formula: C24H28N6OS

Exact Mass: 448.2000

Molecular Weight: 448.59

Elemental Analysis: C, 64.26; H, 6.29; N, 18.73; O, 3.57; S, 7.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Thioquinapiperifil; KF-31327 free base; KF-31327; KF 31327; KF31327;
IUPAC/Chemical Name
3-ethyl-8-((2-(4-(hydroxymethyl)piperidin-1-yl)benzyl)amino)-1,3-dihydro-2H-imidazo[4,5-g]quinazoline-2-thione
InChi Key
NMKUPEWPVORTPC-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H28N6OS/c1-2-30-22-12-19-18(11-20(22)28-24(30)32)23(27-15-26-19)25-13-17-5-3-4-6-21(17)29-9-7-16(14-31)8-10-29/h3-6,11-12,15-16,31H,2,7-10,13-14H2,1H3,(H,28,32)(H,25,26,27)
SMILES Code
NMKUPEWPVORTPC-UHFFFAOYSA-N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 448.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Uchiyama N, Saisho K, Kikura-Hanajiri R, Haishima Y, Goda Y. Determination of a new type of phosphodiesterase-5 inhibitor, thioquinapiperifil, in a dietary supplement promoted for sexual enhancement. Chem Pharm Bull (Tokyo). 2008 Sep;56(9):1331-4. PubMed PMID: 18758113.