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MedKoo Cat#: 592493 | Name: Alclofenac sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Alclofenac sodium is an anti-inflammatory agent used in the treatment of rheumatoid arthritis.

Chemical Structure

Alclofenac sodium
Alclofenac sodium
CAS#24049-18-1

Theoretical Analysis

MedKoo Cat#: 592493

Name: Alclofenac sodium

CAS#: 24049-18-1

Chemical Formula: C11H10ClNaO3

Exact Mass: 248.0216

Molecular Weight: 248.64

Elemental Analysis: C, 53.14; H, 4.05; Cl, 14.26; Na, 9.25; O, 19.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Alclofenac sodium
IUPAC/Chemical Name
(4-(Allyloxy)-3-chlorophenyl)acetic acid sodium salt
InChi Key
JGTGZXFWDPQKBA-UHFFFAOYSA-M
InChi Code
InChI=1S/C11H11ClO3.Na/c1-2-5-15-10-4-3-8(6-9(10)12)7-11(13)14;/h2-4,6H,1,5,7H2,(H,13,14);/q;+1/p-1
SMILES Code
O=C([O-])CC1=CC=C(OCC=C)C(Cl)=C1.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 248.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zecchi V, Rodriguez L, Tartarini A, Fini A. Kinetic aspects of the dissolution and partition of diclofenac, alclofenac and their sodium salts. Arch Pharm (Weinheim). 1984 Nov;317(11):897-905. PubMed PMID: 6151384. 2: Kadir N, Grayson MF, Campbell ED. A double-blind one year clinical trial comparing alclofenac with gold in rheumatoid arthritis. Ann Clin Res. 1983;15(1):4-9. PubMed PMID: 6134490. 3: Ohnishi H, Ito C, Yamaguchi K, Suzuki K, Saito A, Fujimura H. [Comparative study on the pharmacological activities of protizinic acid and various non-steroidal anti-inflammatory agents (author's transl)]. Nihon Yakurigaku Zasshi. 1980 Oct;76(7):609-19. Japanese. PubMed PMID: 7215998. 4: Atkinson DC, Leach EC. Anti-inflammatory and related properties of 2-(2,4-dichlorophenoxy)phenylacetic acid (fenclofenac). Agents Actions. 1976 Sep;6(5):657-66. PubMed PMID: 970297. 5: Aylward M, Maddock J, Wheeldon R, Parker RJ. A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis. Rheumatol Rehabil. 1975 May;14(2):101-14. PubMed PMID: 238274. 6: Evans PH. Serum sulphydryl levels in rheumatoid patients treated with alclofenac. Curr Med Res Opin. 1975;3(5):268-75. PubMed PMID: 241596.