KF 392 | CAS#60671-62-7 | antiulcer agent

MedKoo Cat#: 558489 | Name: KF 392

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KF 392 is an antiulcer agent. It was found that KF-392 given orally to rats at 1.0 to 5.0 mg/kg had a marked suppression on the developments of Shay ulcer as well as the aspirin-, stress-, and reserpine-induced gastric lesions.

Chemical Structure

KF 392

CAS#60671-62-7

Theoretical Analysis

MedKoo Cat#: 558489

Name: KF 392

CAS#: 60671-62-7

Chemical Formula: C8H12N2O4

Exact Mass: 200.0800

Molecular Weight: 200.19

Elemental Analysis: C, 48.00; H, 6.04; N, 13.99; O, 31.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

KF 392; KF-392; KF392;

IUPAC/Chemical Name

3-(Aminocarbonyl)-7-oxabicyclo(2.2.1)hept-5-ene-2-carboxylic acid, monoammonium salt

InChi Key

UTBRKYJEXZKRGY-UHFFFAOYSA-N

InChi Code

InChI=1S/C8H9NO4.H3N/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12;/h1-6H,(H2,9,10)(H,11,12);1H3

SMILES Code

O=C(C1C(O2)C=CC2C1C(N)=O)[O-].[NH4+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 200.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanaka H, Suzuki Y, Kojima T, Marumo H. Influence of a new antiulcer agent, ammonium 7-oxobicyclo (2, 2, 1) hept-5-ene-3-carbamoyl-2-carboxylate (KF-392) on gastric lesions and gastric mucosal barrier in rats. Jpn J Pharmacol. 1976 Aug;26(4):403-10. PubMed PMID: 1003697. 2: Hoppe M, Mikutta R, Utermann J, Duijnisveld W, Guggenberger G. Retention of sterically and electrosterically stabilized silver nanoparticles in soils. Environ Sci Technol. 2014 Nov 4;48(21):12628-35. doi: 10.1021/es5026189. Epub 2014 Oct 15. PubMed PMID: 25251386.