Kujimycin A | CAS#33955-27-0 | macrolide antibiotic

MedKoo Cat#: 598300 | Name: Kujimycin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kujimycin A is a macrolide antibiotics isolated from various strains of Streptomyces; many have significant activity against some Gram positive bacteria.

Chemical Structure

Kujimycin A

CAS#33955-27-0

Theoretical Analysis

MedKoo Cat#: 598300

Name: Kujimycin A

CAS#: 33955-27-0

Chemical Formula: C40H70O15

Exact Mass: 790.4715

Molecular Weight: 790.98

Elemental Analysis: C, 60.74; H, 8.92; O, 30.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Kujimycin A; Desacetyllankamycin;

IUPAC/Chemical Name

(2R,3R,4R,5S,7R,9S,10S,11R,12R,13R)-7-hydroxy-12-(((2S,4S,5R,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2S,3S,4S,6R)-3-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-((2R,3R)-3-hydroxybutan-2-yl)-3,5,7,9,11,13-hexamethyl-6,14-dioxooxacyclotetradecan-4-yl acetate

InChi Key

XITHDKRNUSLORY-HGLCJHSCSA-N

InChi Code

InChI=1S/C40H70O15/c1-18-16-39(11,47)35(44)23(6)33(52-27(10)42)22(5)32(20(3)25(8)41)54-37(46)24(7)34(53-29-17-40(12,49-14)36(45)26(9)51-29)21(4)31(18)55-38-30(43)28(48-13)15-19(2)50-38/h18-26,28-34,36,38,41,43,45,47H,15-17H2,1-14H3/t18-,19+,20+,21+,22+,23-,24+,25+,26-,28-,29+,30-,31-,32+,33+,34+,36+,38-,39+,40-/m0/s1

SMILES Code

C[C@@H]([C@H]([C@H](C(O[C@H]([C@H](C)[C@H](O)C)[C@H]([C@H]([C@H](C)C([C@@](C)(C[C@@H]1C)O)=O)OC(C)=O)C)=O)C)O[C@@H]2C[C@@](OC)(C)[C@H](O)[C@H](C)O2)[C@H]1O[C@@H]3O[C@H](C)C[C@H](OC)[C@@H]3O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 790.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Omura S, Namiki S, Shibata M, Muro T, Sawada J. Studies on the antibiotics from Streptomyces spinichromogenes var. kujimyceticus. V. Some antimicrobial characteristics of kujimycin A and kujimycin B against macrolide resistant staphylococci. J Antibiot (Tokyo). 1970 Sep;23(9):448-60. PubMed PMID: 5202114. 2: Omura S, Muro T, Namiki S, Shibata M, Sawada J. Studies on the antibiotics from Streptomyces spinichromogenes var. kujimyceticus. 3. The structure of kujimycin A and kujimycin B. J Antibiot (Tokyo). 1969 Dec;22(12):629-34. PubMed PMID: 5367395. 3: Omura S, Namiki S, Shibata M, Muro T, Machida S. Antibacterial activity of some acetyl derivatives of kujimycin A. J Antibiot (Tokyo). 1971 Oct;24(10):717-8. PubMed PMID: 5158588. 4: Kobayashi H, Endou K, Nakajima Y. [Inducible resistance to macrolide-lincosamide-streptogramin type B antibiotics in Bacillus licheniformis: common structures of macrolide antibiotics capable of inducing the resistance]. Yakugaku Zasshi. 1993 Mar;113(3):264-71. Japanese. PubMed PMID: 8509994.