N-Boc-PEG2-bromide is a PEG derivative containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
MedKoo Cat#: 572131
Name: N-Boc-PEG2-bromide
CAS#: 165963-71-3
Chemical Formula: C11H22BrNO4
Exact Mass: 311.0732
Molecular Weight: 312.20
Elemental Analysis: C, 42.32; H, 7.10; Br, 25.59; N, 4.49; O, 20.50
The following data is based on the product molecular weight 312.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
