MedKoo Cat#: 461130 | Name: HW 173

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HW 173 is a drug that displays high and specific affinity for sigma receptors; HW 173 is the (trans)-isomer.

Chemical Structure

HW 173
HW 173
CAS#110270-70-7

Theoretical Analysis

MedKoo Cat#: 461130

Name: HW 173

CAS#: 110270-70-7

Chemical Formula: C21H25NO

Exact Mass: 307.1936

Molecular Weight: 307.43

Elemental Analysis: C, 82.04; H, 8.20; N, 4.56; O, 5.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
HW 173; HW-173; HW173;
IUPAC/Chemical Name
(4aR,10bR)-4-benzyl-9-methoxy-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline
InChi Key
NSGMNJDNHSTYBY-TZIWHRDSSA-N
InChi Code
InChI=1S/C21H25NO/c1-23-18-11-9-17-10-12-21-19(20(17)14-18)8-5-13-22(21)15-16-6-3-2-4-7-16/h2-4,6-7,9,11,14,19,21H,5,8,10,12-13,15H2,1H3/t19-,21-/m1/s1
SMILES Code
COc1cc([C@H]2CCCN(Cc3ccccc3)[C@@H]2CC4)c4cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
1: Engberg G, Wikström H. Sigma-receptors: implication for the control of neuronal activity of nigral dopamine-containing neurons. Eur J Pharmacol. 1991 Aug 29;201(2-3):199-202. PubMed PMID: 1686758.

Preparing Stock Solutions

The following data is based on the product molecular weight 307.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL