MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 592451 | Name: Selenalysine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Selenalysine is a lantipeptides used as a scaffold for drug development.

Chemical Structure

Selenalysine
Selenalysine
CAS#57601-68-0

Theoretical Analysis

MedKoo Cat#: 592451

Name: Selenalysine

CAS#: 57601-68-0

Chemical Formula: C5H12N2O2Se

Exact Mass: 212.0064

Molecular Weight: 211.12

Elemental Analysis: C, 28.45; H, 5.73; N, 13.27; O, 15.16; Se, 37.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Selenalysine
IUPAC/Chemical Name
3-((2-Aminoethyl)seleno)alanine
InChi Key
WJAIXCQFCNCZGH-BYPYZUCNSA-N
InChi Code
InChI=1S/C5H12N2O2Se/c6-1-2-10-3-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
SMILES Code
N[C@@H](C[Se]CCN)C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 211.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Seebeck FP, Ricardo A, Szostak JW. Artificial lantipeptides from in vitro translations. Chem Commun (Camb). 2011 Jun 7;47(21):6141-3. doi: 10.1039/c0cc05663d. Epub 2011 Apr 28. PubMed PMID: 21528125. 2: Seebeck FP, Szostak JW. Ribosomal synthesis of dehydroalanine-containing peptides. J Am Chem Soc. 2006 Jun 7;128(22):7150-1. PubMed PMID: 16734454; PubMed Central PMCID: PMC2572134. 3: Coccia R, Foppoli C, Blarzino C, De Marco C, Pensa B. Transamination of some sulphur- or selenium-containing amino acids by bovine liver glutamine transaminase. Physiol Chem Phys Med NMR. 1992;24(4):313-21. PubMed PMID: 1296212. 4: Di Girolamo M, Busiello V, Coccia R, Foppoli C. Aspartokinase III repression and lysine analogs utilization for protein synthesis. Physiol Chem Phys Med NMR. 1990;22(4):241-5. PubMed PMID: 2129308. 5: Di Girolamo M, De Marco C, Blarzino C, Di Girolamo A, Foppoli C, Coccia R, Busiello V, Cini C. Isolation of thialysine--and selenalysine--resistant mutants of E. coli and CHO cells. Ital J Biochem. 1989 Jul-Aug;38(4):271A-273A. PubMed PMID: 2511161. 6: Blarzino C, Coccia R, Foppoli C, Pensa B, De Marco G. Selenalysine transamination by a bovine brain enzyme. Physiol Chem Phys Med NMR. 1989;21(4):295-300. PubMed PMID: 2518711. 7: Di Girolamo M, Coccia R, Blarzino C, Di Girolamo A, Busiello V. Degradation of thialysine- or selenalysine-containing abnormal proteins in E. coli. Biochem Int. 1988 Jun;16(6):1033-40. PubMed PMID: 3140818. 8: Busiello V, Cini C, Coccia R, Di Girolamo A, Di Girolamo M. Thialysine- and selenalysine-resistance in a E. coli mutant. Physiol Chem Phys Med NMR. 1988;20(3):193-7. PubMed PMID: 3149757. 9: Busiello V, Cini C, Di Girolamo A, Di Girolamo M. Utilization of lysine analogs by a lysine-requiring E. coli mutant. Physiol Chem Phys Med NMR. 1988;20(2):109-13. PubMed PMID: 3146758. 10: Di Girolamo M, Busiello V, Di Girolamo A, De Marco C, Cini C. Degradation of thialysine- or selenalysine-containing abnormal proteins in CHO cells. Biochem Int. 1987 Nov;15(5):971-80. PubMed PMID: 3124854. 11: di Girolamo M, Busiello V, di Girolamo A, Cini C, de Marco C. Biochemical characterization of a thialysine-resistant clone of CHO cells. Mutat Res. 1987 Nov;192(3):221-5. PubMed PMID: 2825008. 12: Blarzino C, Coccia R, Busiello V, Di Girolamo A, Di Girolamo M. Thialysine and selenalysine incorporation into CHO cell proteins and its effects on cell growth. Ital J Biochem. 1987 Jul-Aug;36(4):227-32. PubMed PMID: 3123419. 13: Cini C, De Marco C, Di Girolamo A, Foppoli C, Blarzino C, Di Girolamo M. Utilization of selenalysine by thialysine resistant CHO cells. Ital J Biochem. 1987 May-Jun;36(3):181-7. PubMed PMID: 3112037. 14: De Marco C, Cini C, Blarzino C, Busiello V, Di Girolamo M. Selenalysine utilization by CHO cells. Physiol Chem Phys Med NMR. 1987;19(3):153-7. PubMed PMID: 3126505. 15: Busiello V, Di Girolamo A, Cini C, Foppoli C, Di Girolamo M. Intracellular transport of thialysine and selenalysine in CHO cells. Physiol Chem Phys Med NMR. 1987;19(1):23-7. PubMed PMID: 3112812. 16: Di Girolamo M, Coccia R, Di Girolamo A, Busiello V, Foppoli C, Cini C. Effects of selenalysine on thialysine resistant CHO cells. Microbiologica. 1986 Oct;9(4):487-92. PubMed PMID: 3095610. 17: Cini C, Coccia R, Foppoli C, Canini M, Di Girolamo M. Effects of selenalysine on CHO cells. Microbiologica. 1986 Jan;9(1):13-9. PubMed PMID: 2419738. 18: Di Girolamo M, Busiello V, Cini C, Blarzino C, De Marco C. Repression of lysine transport in E. coli KL16. Physiol Chem Phys Med NMR. 1983;15(5):417-23. PubMed PMID: 6425873. 19: Busiello V, Di Girolamo M, Coccia R, Cini C. Transport systems for lysine, thialysine and selenalysine in E. coli KL16. Physiol Chem Phys Med NMR. 1983;15(2):121-5. PubMed PMID: 6420812. 20: Coccia R, Busiello V, Cini C, Foppoli C, Di Girolamo M. Thialysine and selenalysine utilization for protein synthesis by E. coli in comparison with lysine. Ital J Biochem. 1983 Jan-Feb;32(1):19-27. PubMed PMID: 6411652.