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MedKoo Cat#: 598233 | Name: Lagunamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lagunamycin is a novel 5-lipoxygenase inhibitor.

Chemical Structure

Lagunamycin
Lagunamycin
CAS#150693-65-5

Theoretical Analysis

MedKoo Cat#: 598233

Name: Lagunamycin

CAS#: 150693-65-5

Chemical Formula: C19H21N3O4

Exact Mass: 355.1532

Molecular Weight: 355.39

Elemental Analysis: C, 64.21; H, 5.96; N, 11.82; O, 18.01

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lagunamycin;
IUPAC/Chemical Name
(R,E)-6-diazo-4-(4,6-dimethylhept-2-en-2-yl)-3-methylquinoline-2,5,7,8(1H,6H)-tetraone
InChi Key
PJKDXVRDJPKOHU-YIXGCBLDSA-N
InChi Code
InChI=1S/C19H21N3O4/c1-8(2)6-9(3)7-10(4)12-11(5)19(26)21-14-13(12)16(23)15(22-20)18(25)17(14)24/h7-9H,6H2,1-5H3,(H,21,26)/b10-7+/t9-/m1/s1
SMILES Code
O=C1NC2=C(C(C(C(C2=O)=O)=[N+]=[N-])=O)C(/C(C)=C/[C@H](C)CC(C)C)=C1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 355.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nihei Y, Hasegawa M, Suzuki K, Yamamoto S, Hanada M, Furumai T, Fukagawa Y, Oki T. Lagunamycin, a novel 5-lipoxygenase inhibitor. I. Taxonomy, fermentation, physico-chemical properties and biological characteristics. J Antibiot (Tokyo). 1993 Jun;46(6):900-7. PubMed PMID: 8393850. 2: Imae K, Nihei Y, Oka M, Yamasaki T, Konishi M, Oki T. Lagunamycin, a novel 5-lipoxygenase inhibitor. II. Structural studies. J Antibiot (Tokyo). 1993 Jun;46(6):1031-3. PubMed PMID: 8393849. 3: Tatsuta K, Hosokawa S. Total syntheses of polyketide-derived bioactive natural products. Chem Rec. 2006;6(4):217-33. Review. PubMed PMID: 16900486. 4: Díaz-Cárdenas C, Cantillo A, Rojas LY, Sandoval T, Fiorentino S, Robles J, Ramos FA, Zambrano MM, Baena S. Microbial diversity of saline environments: searching for cytotoxic activities. AMB Express. 2017 Dec 22;7(1):223. doi: 10.1186/s13568-017-0527-6. Erratum in: AMB Express. 2018 Mar 9;8(1):35. PubMed PMID: 29273919; PubMed Central PMCID: PMC5741568.