Diflumidone | CAS#22736-85-2 | antiinflammatory

MedKoo Cat#: 461094 | Name: Diflumidone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diflumidone is a non-steroidal antiinflammatory drug.

Chemical Structure

Diflumidone

CAS#22736-85-2

Theoretical Analysis

MedKoo Cat#: 461094

Name: Diflumidone

CAS#: 22736-85-2

Chemical Formula: C14H11F2NO3S

Exact Mass: 311.0428

Molecular Weight: 311.30

Elemental Analysis: C, 54.02; H, 3.56; F, 12.21; N, 4.50; O, 15.42; S, 10.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Diflumidone; R 807; R-807; R807;

IUPAC/Chemical Name

N-(3-benzoylphenyl)-1,1-difluoromethanesulfonamide

InChi Key

JLBDOSAQLCZTSX-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H11F2NO3S/c15-14(16)21(19,20)17-12-8-4-7-11(9-12)13(18)10-5-2-1-3-6-10/h1-9,14,17H

SMILES Code

O=S(Nc1cc(C(c2ccccc2)=O)ccc1)(C(F)F)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 311.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gomez EC, Trancik RJ. Effect of topical diflumidone on ultraviolet-light-induced erythema. Dermatologica. 1981;162(3):175-82. PubMed PMID: 7250461. 2: Xiong HY, Bayle A, Pannecoucke X, Besset T. An Electrophilic Reagent for the Direct Introduction of the SCF(2) PO(OEt)(2) Group to Molecules. Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13490-13494. doi: 10.1002/anie.201607231. Epub 2016 Sep 26. PubMed PMID: 27667673. 3: Vigdahl RL, Tukey RH. Mechanism of action of novel anti-inflammmatory drugs diflumidone and R-805. Biochem Pharmacol. 1977 Feb 15;26(4):307-11. PubMed PMID: 403918. 4: Swingle KF, Hamilton RR, Harrington JK, Kvam DC. 3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent. Arch Int Pharmacodyn Ther. 1971 Jan;189(1):129-44. PubMed PMID: 5130145.