MedKoo Cat#: 461063 | Name: Butanserin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Butanserin is a 5-hydroxytryptamine S2-antagonist.

Chemical Structure

Butanserin
Butanserin
CAS#87051-46-5

Theoretical Analysis

MedKoo Cat#: 461063

Name: Butanserin

CAS#: 87051-46-5

Chemical Formula: C21H24FN3O2S

Exact Mass: 401.1573

Molecular Weight: 401.50

Elemental Analysis: C, 62.82; H, 6.03; F, 4.73; N, 10.47; O, 7.97; S, 7.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Butanserin; R 53393; R-53393; R53393;
IUPAC/Chemical Name
6-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-7-methyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one
InChi Key
RBGAHDDQSRBDOG-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H24FN3O2S/c1-14-18(20(27)25-12-13-28-21(25)23-14)8-11-24-9-6-16(7-10-24)19(26)15-2-4-17(22)5-3-15/h2-5,16H,6-13H2,1H3
SMILES Code
O=C1C(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)=C(C)N=C4N1CCS4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Megens AA, Niemegeers CJ. Antagonism of the antidiarrhoeal effect of clonidine and the lethal effect of noradrenaline in rats: a reliable procedure to evaluate the in-vivo alpha 1- and alpha 2-blocking activity of drugs? J Pharm Pharmacol. 1984 Aug;36(8):516-20. PubMed PMID: 6148393. 2: Korstanje C, Sprenkels R, Doods HN, Hugtenburg JG, Boddeke E, Batink HD, Thoolen MJ, Van Zwieten PA. Characterization of flufylline, fluprofylline, ritanserin, butanserin and R 56413 with respect to in-vivo alpha 1-,alpha 2- and 5-HT2-receptor antagonism and in-vitro affinity for alpha 1-,alpha 2- and 5-HT2-receptors: comparison with ketanserin. J Pharm Pharmacol. 1986 May;38(5):374-9. PubMed PMID: 2872314.