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MedKoo Cat#: 598171 | Name: Bisoxatin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bisoxatin can be used in analytical study for detection of laxative abuse by urine analysis with HPLC and diode array detection. Bisoxatin is also medicine for Laxatives.

Chemical Structure

Bisoxatin
Bisoxatin
CAS#17692-24-9

Theoretical Analysis

MedKoo Cat#: 598171

Name: Bisoxatin

CAS#: 17692-24-9

Chemical Formula: C20H15NO4

Exact Mass: 333.1001

Molecular Weight: 333.34

Elemental Analysis: C, 72.06; H, 4.54; N, 4.20; O, 19.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Bisoxatin; LA 271A; LA-271A; LA271A;
IUPAC/Chemical Name
2,2-bis(4-hydroxyphenyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
InChi Key
BPKUDUSVDVLOPY-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H15NO4/c22-15-9-5-13(6-10-15)20(14-7-11-16(23)12-8-14)19(24)21-17-3-1-2-4-18(17)25-20/h1-12,22-23H,(H,21,24)
SMILES Code
O=C1C(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)OC4=CC=CC=C4N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 333.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rider JA. Treatment of acute and chronic constipation with bisoxatin acetate and bisacodyl. Double-blind crossover study. Curr Ther Res Clin Exp. 1971 Jun;13(6):386-92. PubMed PMID: 4996225. 2: Diamond RA, Gall SA, Spellacy WN. Bisoxatin acetate as a postpartum oral laxative: a random double blind controlled experiment in 106 subjects. J Lancet. 1968 Jan;88(1):16-7. PubMed PMID: 4865759. 3: de Wolff FA, Edelbroek PM, de Haas EJ, Vermeij P. Experience with a screening method for laxative abuse. Hum Toxicol. 1983 Apr;2(2):385-9. PubMed PMID: 6862485. 4: Fullinfaw RO, Bury RW, Moulds RF. Screening procedure for stimulant laxatives in urine using high-performance liquid chromatography with diode array detection. J Chromatogr. 1988 Dec 9;433:131-40. PubMed PMID: 3235541. 5: Mattivi G, Scoz R, Donner C. [Treatment of chronic constipation with a contact laxative in pearl form: bisoxatin acetate]. Atti Accad Med Lomb. 1972;27(1-4):127-33. Italian. PubMed PMID: 4681351. 6: de Wolff FA, de Haas EJ, Verweij M. A screening method for establishing laxative abuse. Clin Chem. 1981 Jun;27(6):914-7. PubMed PMID: 6894566. 7: de Lima de Mon M, Cioccia AM, González E, Hevia P. [Effects of secretory and osmotic diarrhea on rats intestinal function and morphology]. Arch Latinoam Nutr. 2002 Mar;52(1):20-8. Spanish. PubMed PMID: 12214542.