MedKoo Cat#: 592393 | Name: Pseudoakuammigine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pseudoakuammigine is a biochemical.

Chemical Structure

 Pseudoakuammigine
Pseudoakuammigine
CAS#2447-70-3

Theoretical Analysis

MedKoo Cat#: 592393

Name: Pseudoakuammigine

CAS#: 2447-70-3

Chemical Formula: C22H26N2O3

Exact Mass: 366.1943

Molecular Weight: 366.46

Elemental Analysis: C, 72.11; H, 7.15; N, 7.64; O, 13.10

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Pseudoakuammigine; NSC 381082; NSC-381082; NSC381082
IUPAC/Chemical Name
Akuammine, 10-deoxy-
InChi Key
HAGBWVNSVWLTKY-ZFWLQQAWSA-N
InChi Code
InChI=1S/C22H26N2O3/c1-4-14-12-24-10-9-21-15-7-5-6-8-17(15)23(2)22(21)18(24)11-16(14)20(21,13-27-22)19(25)26-3/h4-8,16,18H,9-13H2,1-3H3/b14-4-/t16-,18-,20-,21-,22+/m0/s1
SMILES Code
COC([C@]12CO[C@]34[C@@H]5C[C@H]1/C(CN5CC[C@]23c6c(N4C)cccc6)=C\C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 366.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Andreansky ES, Blakey SB. An Iminium Ion Cascade Annulation Strategy for the Synthesis of Akuammiline Alkaloid Pentacyclic Core Structures. Org Lett. 2016 Dec 16;18(24):6492-6495. Epub 2016 Dec 1. PubMed PMID: 27978638. 2: Ramírez A, García-Rubio S. Current progress in the chemistry and pharmacology of akuammiline alkaloids. Curr Med Chem. 2003 Sep;10(18):1891-915. Review. PubMed PMID: 12871110. 3: Menzies JR, Paterson SJ, Duwiejua M, Corbett AD. Opioid activity of alkaloids extracted from Picralima nitida (fam. Apocynaceae). Eur J Pharmacol. 1998 May 29;350(1):101-8. PubMed PMID: 9683021. 4: Hu WL, Zhu JP, Hesse M. Indole Alkaloids from Alstonia angustifolia. Planta Med. 1989 Oct;55(5):463-6. PubMed PMID: 17262459. 5: Balsevich J, Constabel F, Kurz WG. Alkaloids of Vinca major cv. Variegata. Planta Med. 1982 Feb;44(2):91-3. PubMed PMID: 17402086.