AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
MedKoo Cat#: 592356
Name: AKB-6899
CAS#: 1007377-55-0
Chemical Formula: C14H11FN2O4
Exact Mass: 290.0703
Molecular Weight: 290.25
Elemental Analysis: C, 57.93; H, 3.82; F, 6.55; N, 9.65; O, 22.05
The following data is based on the product molecular weight 290.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
