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MedKoo Cat#: 592353 | Name: Akagerine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Akagerine is a biochemical that is derived from the root bark of South American Strychnos.

Chemical Structure

Akagerine
Akagerine
CAS#56519-07-4

Theoretical Analysis

MedKoo Cat#: 592353

Name: Akagerine

CAS#: 56519-07-4

Chemical Formula: C20H24N2O2

Exact Mass: 324.1838

Molecular Weight: 324.42

Elemental Analysis: C, 74.05; H, 7.46; N, 8.63; O, 9.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Akagerine
IUPAC/Chemical Name
3,7a-Diazacyclohepta(jk)fluorene-5-acetaldehyde, alpha-ethylidene-1,2,3,3a,4,5,6,7-octahydro-7-hydroxy-3-methyl-, (3aS-(3aalpha,5beta(E),7alpha))-
InChi Key
LGSDYQBPJKYJCT-YTLNUPAMSA-N
InChi Code
InChI=1S/C20H24N2O2/c1-3-13(12-23)14-10-18-20-16(8-9-21(18)2)15-6-4-5-7-17(15)22(20)19(24)11-14/h3-7,12,14,18-19,24H,8-11H2,1-2H3/b13-3-/t14-,18+,19+/m1/s1
SMILES Code
O=C/C([C@H](C1)C[C@H](O)N2C3=C(C4=C2[C@@]1([H])N(C)CC4)C=CC=C3)=C/C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 324.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Thongphasuk P, Suttisri R, Bavovada R, Verpoorte R. Alkaloids and a pimarane diterpenoid from Strychnos vanprukii. Phytochemistry. 2003 Oct;64(4):897-901. PubMed PMID: 14559288. 2: Brandt V, Tits M, Penelle J, Frédérich M, Angenot L. Main glucosidase conversion products of the gluco-alkaloids dolichantoside and palicoside. Phytochemistry. 2001 Jul;57(5):653-9. PubMed PMID: 11397430. 3: Wright CW, Bray DH, O'Neill MJ, Warhurst DC, Phillipson JD, Quetin-Leclercq J, Angenot L. Antiamoebic and antiplasmodial activities of alkaloids isolated from Strychnos usambarensis. Planta Med. 1991 Aug;57(4):337-40. PubMed PMID: 1775573. 4: Verpoorte R, Joosse FT, Groenink H, Svendsen AB. Alkaloids from Strychnos floribunda. Planta Med. 1981 May;42(1):32-6. PubMed PMID: 17401877. 5: Marini-Bettolo GB, Messana I, Nicoletti M, Patamia M, Galeffi C. On the alkaloids of Strychnos. XXXV. The occurrence of akagerine in South American Strychnos. J Nat Prod. 1980 Nov;43(6):717-20. doi: 10.1021/np50012a003. PubMed PMID: 20000812. 6: Rolfsen WN, Olaniyi AA, Hylands PJ. New tertiary alkaloids of Strychnos decussata. J Nat Prod. 1980 Jan-Feb;43(1):97-102. PubMed PMID: 7400820.